Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | EDNRB | P24530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7638200 | 0.82 | MAPT (0.33) | KDM4EALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL7636034 | 0.80 | KDM4E (0.33) | KDM4EALDH1A1MAPTHPGDMAPK1 | |
| Hydrochloric Acid SCHEMBL7638205 | 0.78 | KDM4E (0.31) | KDM4EALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL5859267 | 0.74 | KDM4E (0.36) | SLC6A3KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL6064691 | 0.74 | HTR6 (0.33) | CYP2D6SLC6A2SLC6A3KDM4EALDH1A1 | |
| SCHEMBL7811624 | 0.73 | ALDH1A1 (0.33) | CYP2D6SLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL17386685 | 0.72 | MAPK1 (0.33) | MTNR1AMTNR1BCYP2D6SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL7644118 | 0.72 | MTNR1A (0.32) | MTNR1AMTNR1BCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL7646636 | 0.72 | SLC6A4 (0.35) | CYP2D6SLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL5352323 | 0.71 | MAPT (0.32) | MTNR1AMTNR1BCYP2D6SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670681-A | Process for preparing a carbon-bridged biscyclopentadiene compound | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |