Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.53 |
| ▸ | CASP3 | P42574 | 2/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.53 |
| ▸ | APAF1 | O14727 | 1/20 | 0.53 |
| ▸ | TDP2 | O95551 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8856938 | 0.85 | MAPT (0.56) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL8856666 | 0.81 | SENP6 (0.61) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL8856569 | 0.81 | MAPT (0.60) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL8856756 | 0.81 | MAPT (0.54) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL8856560 | 0.79 | MAPT (0.68) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL6977823 | 0.75 | ALDH1A1 (0.44) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL8856994 | 0.75 | MAPT (0.59) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL8667830 | 0.74 | SENP6 (0.61) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL8856708 | 0.73 | MAPT (0.56) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL9004676 | 0.73 | ALDH1A1 (0.55) | MAPTKMT2ANPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130287727-A1 | Psyllid Attractants and Their Uses | INSCENT, INC. (US) | 2013-10-31 | — | — | US | disclosed |
| US-20130287727-A1 | Psyllid Attractants and Their Uses | INSCENT, INC. (US) | 2013-10-31 | — | — | US | disclosed |
| US-20130287727-A1 | Psyllid Attractants and Their Uses | INSCENT, INC. (US) | 2013-10-31 | — | — | US | disclosed |
| US-5648381-A | Derivatives of indan-1,3-dione and indan-1,2,3-trione, methods of preparing them and therapeutic use thereof | INNOTHERA (FR) | 1997-07-15 | — | — | US | disclosed |
| EP-0566446-B1 | Derivatives of indane-1,3-dione and indane-1,2,3-trione, processes for their preparation and their application in therapy | INNOTHERA LAB SA (FR) | 1996-02-07 | — | — | EP | disclosed |
| EP-0566446-A1 | Derivatives of indane-1,3-dione and indane-1,2,3-trione, processes for their preparation and their application in therapy | INNOTHERA (FR) | 1993-10-20 | — | — | EP | disclosed |
| WO-1993020046-A1 | INDAN-1,3-DIONE AND INDAN-1,2,3-TRIONE DERIVATIVES, PROCESSES FOR PREPARATION OF SAME AND THEIR USE AS THERAPEUTIC AGENTS | INNOTHERA (FR) | 1993-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130287727-A1 | Psyllid Attractants and Their Uses | L3MBTL3, LPAR3, LPXN | MAPT 2211/4885KMT2A 1612/4885NPC1 3023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.