Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8982044 | 0.91 | CYP3A4 (0.40) | MAOBMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8146444 | 0.83 | SLC6A2 (0.42) | MAOBMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8961286 | 0.83 | SLC6A2 (0.42) | MAOBMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10479865 | 0.82 | SLC6A2 (0.41) | MAOBMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10479867 | 0.82 | SLC6A2 (0.41) | MAOBMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9809556 | 0.81 | MAOB (0.40) | MAOBMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2392780 | 0.80 | CYP2C9 (0.49) | SLC6A4CYP2C9OPRM1OPRK1OPRL1 | |
| SCHEMBL6558027 | 0.80 | CYP2C9 (0.49) | SLC6A4CYP2C9OPRM1OPRK1OPRL1 | |
| SCHEMBL30400657 | 0.80 | CYP2C9 (0.49) | SLC6A4CYP2C9OPRM1OPRK1OPRL1 | |
| SCHEMBL2483099 | 0.80 | LPL (0.52) | LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637257-A | LIQUID CRYSTAL DISPLAYING | MERCK PATENT GESELLSCHAFT MLT BESCHRANKTER HAFTUNG (DE) | 1997-06-10 | — | — | US | disclosed |
| US-5482653-A | FOR LIQUID CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-01-09 | — | — | US | disclosed |
| WO-1990015113-A1 | FLUORO-CHLORO-BENZENE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-12-13 | — | — | WO | disclosed |