Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309955 | 0.92 | ITGB3 (0.37) | KDM4EMEN1KMT2AITGB3ITGA2B | |
| SCHEMBL8858181 | 0.91 | L3MBTL1 (0.34) | KDM4EMEN1KMT2AITGB3ITGA2B | |
| SCHEMBL8858111 | 0.90 | LMNA (0.41) | KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8858107 | 0.88 | KDM4E (0.33) | KDM4EMEN1KMT2AITGB3ITGA2B | |
| SCHEMBL8858063 | 0.86 | ITGB3 (0.34) | KDM4EMEN1KMT2AITGB3ITGA2B | |
| SCHEMBL8858116 | 0.86 | KDM4E (0.35) | KDM4EMEN1KMT2AITGB3ITGA2B | |
| SCHEMBL8858095 | 0.86 | MEN1 (0.37) | KDM4EMEN1KMT2AITGB3ITGA2B | |
| SCHEMBL8858191 | 0.85 | MEN1 (0.42) | KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8858178 | 0.85 | MEN1 (0.41) | KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8858082 | 0.84 | KDM4E (0.34) | KDM4EMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627197-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-05-06 | — | — | US | disclosed |