Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.61 |
| ▸ | HTR2A | P28223 | 3/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.53 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.53 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.53 |
| ▸ | SLC22A3 | O75751 | 2/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.53 |
| ▸ | HRH1 | P35367 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | SCN1A | P35498 | 2/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.53 |
| ▸ | HTR2B | P41595 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9083641 | 0.84 | SLC6A1 (0.51) | SLC6A4HTR2AMEN1KMT2ASLC6A1 | |
| SCHEMBL6961973 | 0.83 | HTR2A (0.68) | SLC6A4HTR2ASLC6A2SLC22A2SLC22A1 | |
| SCHEMBL7168298 | 0.82 | HTR2A (0.66) | SLC6A4HTR2ASLC6A2SLC22A2SLC22A1 | |
| SCHEMBL6637686 | 0.79 | HTR2A (0.61) | SLC6A4HTR2ASLC6A2SLC22A2SLC22A1 | |
| SCHEMBL13051501 | 0.79 | HTR2A (0.78) | SLC6A4HTR2ASLC6A2SLC22A2SLC22A1 | |
| SCHEMBL14140510 | 0.79 | HTR2A (0.62) | SLC6A4HTR2ASLC6A2SLC22A2SLC22A1 | |
| SCHEMBL5711008 | 0.78 | ALDH1A1 (0.44) | SLC6A4HTR2ASLC6A2CHRM2CHRM1 | |
| SCHEMBL8201084 | 0.77 | HTR2A (0.59) | SLC6A4HTR2ASLC6A2SLC22A2SLC22A1 | |
| SCHEMBL11376146 | 0.76 | HTR2A (0.54) | SLC6A4HTR2ASLC6A2SLC22A2SLC22A1 | |
| SCHEMBL11376142 | 0.75 | HTR2A (0.57) | SLC6A4HTR2ASLC6A2SLC22A2SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997022342-A1 | NOVEL METHOD | NOVO NORDISK A/S (DK) | 1997-06-26 | — | — | WO | disclosed |
| EP-0585314-B1 | NOVEL HETEROCYCLIC CARBOXYLIC ACIDS | NOVO NORDISK AS (DK) | 1996-09-18 | — | — | EP | disclosed |
| US-5348965-A | N-substituted azaheterocyclic carboxylic acids | NOVO NORDISK A/S (DK) | 1994-09-20 | — | — | US | disclosed |
| EP-0585314-A1 | NOVEL HETEROCYCLIC CARBOXYLIC ACIDS. | NOVO NORDISK AS (DK) | 1994-03-09 | — | — | EP | disclosed |
| WO-1992020658-A1 | NOVEL HETEROCYCLIC CARBOXYLIC ACIDS | NOVO NORDISK A/S (DK) | 1992-11-26 | — | — | WO | disclosed |