Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TK1 | P04183 | 7/20 | 0.32 |
| ▸ | TOP2A | P11388 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922853 | 0.87 | TK2 (0.34) | ALDH1A1NPSR1TK1 | |
| SCHEMBL888124 | 0.87 | TK1 (0.37) | ALDH1A1NPSR1TK1POLB | |
| SCHEMBL8904852 | 0.85 | ALDH1A1 (0.33) | ALDH1A1NPSR1TK1TOP2A | |
| SCHEMBL8859641 | 0.81 | TK1 (0.34) | ALDH1A1NPSR1TK1 | |
| SCHEMBL27218401 | 0.80 | RNASE1 (0.33) | ALDH1A1NPSR1TK1 | |
| SCHEMBL8424228 | 0.80 | ALDH1A1 (0.35) | ALDH1A1NPSR1TK1 | |
| SCHEMBL8905512 | 0.77 | ALDH1A1 (0.36) | ALDH1A1NPSR1TK1 | |
| SCHEMBL2056759 | 0.77 | TK1 (0.39) | ALDH1A1NPSR1TK1 | |
| SCHEMBL8906740 | 0.77 | TK1 (0.36) | ALDH1A1NPSR1TK1 | |
| SCHEMBL8859637 | 0.77 | RNASE1 (0.34) | TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625050-A | Modified oligonucleotides and intermediates useful in nucleic acid therapeutics | AMGEN INC. (US) | 1997-04-29 | — | — | US | disclosed |