Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL888124 | 0.82 | TK1 (0.37) | TK1ALDH1A1NPSR1 | |
| SCHEMBL8859638 | 0.81 | ALDH1A1 (0.35) | TK1ALDH1A1NPSR1 | |
| SCHEMBL8904852 | 0.78 | ALDH1A1 (0.33) | TK1ALDH1A1NPSR1 | |
| SCHEMBL27218401 | 0.74 | RNASE1 (0.33) | TK1ALDH1A1NPSR1 | |
| SCHEMBL8744160 | 0.73 | TK1 (0.36) | TK1 | |
| SCHEMBL2056759 | 0.73 | TK1 (0.39) | TK1ALDH1A1NPSR1 | |
| SCHEMBL9216459 | 0.73 | ALDH1A1 (0.35) | TK1ALDH1A1NPSR1 | |
| SCHEMBL8859637 | 0.73 | RNASE1 (0.34) | TK1 | |
| SCHEMBL18670742 | 0.72 | P2RY6 (0.38) | TK1 | |
| SCHEMBL8424864 | 0.72 | ALDH1A1 (0.35) | TK1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625050-A | Modified oligonucleotides and intermediates useful in nucleic acid therapeutics | AMGEN INC. (US) | 1997-04-29 | — | — | US | disclosed |