SCHEMBL8859810

SCHEMBL8859810

NC(=O)CCCCC(N)=O.NCCN1CCNCC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.46
ALOX15 P16050 1/20 0.43
CXCR4 P61073 2/20 0.40
HRH2 P25021 1/20 0.38
HRH1 P35367 1/20 0.38
POLB P06746 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HSD17B10 Q99714 1/20 0.37
ANPEP P15144 1/20 0.36
ERAP2 Q6P179 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SIGMAR1 Q99720 1/20 0.35
CHRM5 P08912 1/20 0.35
CHRM3 P20309 1/20 0.35
GNAI3 P08754 1/20 0.35
GNAO1 P09471 1/20 0.35
GNAI1 P63096 1/20 0.35
LMNA P02545 1/20 0.35
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1076280 0.89 CXCR4 (0.50) L3MBTL1CXCR4HRH2HRH1POLB
Adipic Acid SCHEMBL8433509 0.87 CYP1A2 (0.47) ALOX15CXCR4SMN1; SMN2MEN1KMT2A
Adipic Acid SCHEMBL8962598 0.87 CYP1A2 (0.47) ALOX15CXCR4SMN1; SMN2MEN1KMT2A
SCHEMBL15743490 0.87 CXCR4 (0.53) L3MBTL1ALOX15CXCR4HRH2HRH1
SCHEMBL613914 0.86 L3MBTL1 (0.50) L3MBTL1CXCR4HRH2HRH1POLB
Carbamic Acid SCHEMBL10977422 0.86 ALOX15 (0.48) L3MBTL1ALOX15CXCR4POLBSMN1; SMN2
Acetamide SCHEMBL27808229 0.85 ALOX15 (0.46) L3MBTL1ALOX15CXCR4POLBSMN1; SMN2
SCHEMBL28716335 0.85 L3MBTL1 (0.48) L3MBTL1CXCR4HRH2HRH1POLB
SCHEMBL28706410 0.85 L3MBTL1 (0.48) L3MBTL1CXCR4HRH2HRH1POLB
Bicarbonate SCHEMBL16668577 0.84 ALOX15 (0.50) ALOX15CXCR4POLBSMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0468519-B1 Dyeable hot-bulked polypropylene fibers modified with a copolyamide DU PONT (US) 1996-02-14 EP claimed
US-5130069-A Melt extrusion, stretching E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-07-14 US claimed
EP-0468519-A1 Dyeable hot-bulked polypropylene fibers modified with a copolyamide E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-01-29 EP claimed
WO-1997047684-A1 DYEABLE AND PRINTABLE POLYPROPYLENE COMPOSITION AND PRODUCTS MANUFACTURED THEREOF WETENSCHAPPELIJK EN TECHNISCH CENTRUM VAN DE BELGISCHE TEXTIELNIJVERHEID (CENTEXBEL) (BE) 1997-12-18 WO disclosed