Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | PI4KA | P42356 | 3/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.40 |
| ▸ | SLC28A2 | O43868 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.40 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.40 |
| ▸ | GAPDH | P04406 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | STAT6 | P42226 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1723481 | 0.83 | ADORA3 (0.47) | EGFRADORA3ADORA2API4KAPI4K2B | |
| SCHEMBL11516446 | 0.82 | PI4KA (0.47) | EGFRADORA3ADORA2API4KAPI4K2B | |
| SCHEMBL939590 | 0.81 | ADORA3 (0.54) | EGFRADORA3ADORA2API4KAPI4K2B | |
| SCHEMBL6569314 | 0.79 | ADORA3 (0.52) | EGFRADORA3ADORA2API4KAPI4K2B | |
| Niacinamide SCHEMBL8447045 | 0.79 | EGFR (0.47) | EGFRSRCKDRADORA3ADORA2A | |
| SCHEMBL30198845 | 0.79 | ADORA3 (0.50) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| Niacinamide SCHEMBL8447047 | 0.78 | EGFR (0.47) | EGFRSRCKDRADORA3ADORA2A | |
| SCHEMBL10441571 | 0.78 | ADORA3 (0.50) | EGFRADORA3ADORA2API4KAPI4K2B | |
| SCHEMBL703597 | 0.77 | ADORA3 (0.46) | EGFRADORA3ADORA2API4KAPI4K2B | |
| SCHEMBL28715703 | 0.77 | ADORA3 (0.50) | EGFRADORA3ADORA2API4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9248200-A | — | — | None | — | — | JP | disclosed |
| WO-1997042961-A1 | PHARMACOLOGICAL ASSOCIATION BETWEEN N-ACETYLCYSTEIN AND LEVULOSE FOR PREVENTING CELLULAR DEATH AND RELATED DISEASES | ZAMBON, S.A. (ES) | 1997-11-20 | — | — | WO | disclosed |
| JP-H09248200-A | REAGENT FOR ASSAYING GLUCOSE | NISSHO CORP | 1997-09-22 | — | — | JP | disclosed |