Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | GAA | P10253 | 8/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | GLA | P06280 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | CASP7 | P55210 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.47 |
| ▸ | HTR3B | O95264 | 4/20 | 0.47 |
| ▸ | HTR3A | P46098 | 4/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10339690 | 0.77 | KDM4E (0.63) | ALDH1A1GAAKDM4EGLAHPGD | |
| SCHEMBL4495624 | 0.73 | KDM4E (0.63) | ALDH1A1GAAKDM4EGLAHPGD | |
| SCHEMBL30286612 | 0.73 | GAA (0.57) | ALDH1A1GAAKDM4EGLAHPGD | |
| SCHEMBL3341910 | 0.73 | GAA (0.57) | ALDH1A1GAAKDM4EGLAHPGD | |
| SCHEMBL839837 | 0.72 | ALDH1A1 (0.62) | ALDH1A1GAAKDM4EGLAHPGD | |
| SCHEMBL12145470 | 0.70 | CYP3A4 (0.44) | ALDH1A1KDM4EHPGDNPC1HSD17B10 | |
| SCHEMBL8570625 | 0.70 | HTR3E (0.55) | ALDH1A1GAAKDM4EGLAHPGD | |
| SCHEMBL26907050 | 0.69 | KDM4E (0.57) | ALDH1A1GAAKDM4EGLAHPGD | |
| SCHEMBL8394213 | 0.68 | KDM4E (0.65) | ALDH1A1GAAKDM4EGLAHPGD | |
| SCHEMBL1104759 | 0.68 | MET (0.43) | ALDH1A1GAAKDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639873-A | Oligothionucleotides | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1997-06-17 | — | — | US | claimed |
| EP-0290583-B1 | $g(a) OLIGONUCLEOTIDES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1993-04-07 | — | — | EP | claimed |
| EP-0214908-B1 | COMPOUNDS CONTAINING AN OLIGONUCLEOTIDE SEQUENCE LINKED TO AN INTERCALATING AGENT AND TO AN ACTIVABLE CHEMICAL GROUP, THEIR SYNTHESIS AND APPLICATIONS TO ARTIFICIAL SEQUENCE-SPECIFIC NUCLEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1990-11-07 | — | — | EP | claimed |
| US-5639873-A | Oligothionucleotides | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1997-06-17 | — | — | US | disclosed |
| US-5563132-A | Two-step cancer treatment method | BODANESS RICHARD S (US) | 1996-10-08 | — | — | US | disclosed |
| EP-0118913-B1 | PORPHYRIN DERIVATIVES | Shudo, Koichi, Prof. Dr. (JP) | 1989-06-21 | — | — | EP | disclosed |
| US-4658023-A | ANTITUMOR AGENTS | SHUDO KOICHI (JP) | 1987-04-14 | — | — | US | disclosed |
| US-4658023-A | ANTITUMOR AGENTS | SHUDO KOICHI (JP) | 1987-04-14 | — | — | US | disclosed |
| EP-0118913-A2 | Porphyrin derivatives | Shudo, Koichi, Prof. Dr. (JP) | 1984-09-19 | — | — | EP | disclosed |