Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 3/20 | 0.84 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.68 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.68 |
| ▸ | P2RY11 | Q96G91 | 3/20 | 0.68 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.68 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.68 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.68 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.68 |
| ▸ | ENTPD2 | Q9Y5L3 | 1/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29614811 | 0.92 | P2RX3 (1.00) | P2RX3P2RY12P2RY1P2RY11ENPP1 | |
| SCHEMBL6514575 | 0.92 | P2RX3 (1.00) | P2RX3P2RY12P2RY1P2RY11ENPP1 | |
| SCHEMBL6514561 | 0.92 | P2RX3 (1.00) | P2RX3P2RY12P2RY1P2RY11ENPP1 | |
| SCHEMBL3318315 | 0.84 | P2RX3 (0.78) | P2RX3P2RY12P2RY1P2RY11ENPP1 | |
| SCHEMBL375602 | 0.81 | P2RY1 (1.00) | P2RX3P2RY12P2RY1P2RY11ENPP1 | |
| SCHEMBL10120953 | 0.81 | P2RY1 (1.00) | P2RX3P2RY12P2RY1P2RY11ENPP1 | |
| SCHEMBL29381860 | 0.81 | P2RY1 (1.00) | P2RX3P2RY12P2RY1P2RY11ENPP1 | |
| SCHEMBL375601 | 0.81 | P2RY1 (1.00) | P2RX3P2RY12P2RY1P2RY11ENPP1 | |
| SCHEMBL8861621 | 0.81 | P2RX3 (0.73) | P2RX3P2RY12P2RY1P2RY11ENPP1 | |
| SCHEMBL8861627 | 0.81 | P2RX3 (0.73) | P2RX3P2RY12P2RY1P2RY11ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5620676-A | ADENOSINE TRIPHOSPHATE DERIVATIVES; TREATMENT OF SEPTIC SHOCK OR BRAIN SEIZURES, LEARNING ENHANCEMENT | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1997-04-15 | — | — | US | disclosed |