SCHEMBL29614811

SCHEMBL29614811

Nc1ccc(CCSc2nc(N)c3ncn([C@@H]4O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]4O)c3n2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
P2RX3 P56373 3/20 1.00
P2RY12 Q9H244 4/20 0.74
P2RY1 P47900 4/20 0.74
P2RY11 Q96G91 3/20 0.74
ENPP1 P22413 2/20 0.74
P2RX1 P51575 1/20 0.74
P2RY6 Q15077 1/20 0.74
P2RX4 Q99571 1/20 0.74
ENTPD2 Q9Y5L3 1/20 0.64
ADORA3 P0DMS8 1/20 0.62
GPR17 Q13304 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6514575 1.00 P2RX3 (1.00) P2RX3P2RY12P2RY1P2RY11ENPP1
SCHEMBL6514561 1.00 P2RX3 (1.00) P2RX3P2RY12P2RY1P2RY11ENPP1
SCHEMBL8861601 0.92 P2RX3 (0.84) P2RX3P2RY12P2RY1P2RY11ENPP1
SCHEMBL3318315 0.88 P2RX3 (0.78) P2RX3P2RY12P2RY1P2RY11ENPP1
SCHEMBL375601 0.85 P2RY1 (1.00) P2RX3P2RY12P2RY1P2RY11ENPP1
SCHEMBL375602 0.85 P2RY1 (1.00) P2RX3P2RY12P2RY1P2RY11ENPP1
SCHEMBL10120953 0.85 P2RY1 (1.00) P2RX3P2RY12P2RY1P2RY11ENPP1
SCHEMBL29381860 0.85 P2RY1 (1.00) P2RX3P2RY12P2RY1P2RY11ENPP1
SCHEMBL8861621 0.84 P2RX3 (0.73) P2RX3P2RY12P2RY1P2RY11ENPP1
SCHEMBL8861627 0.84 P2RX3 (0.73) P2RX3P2RY12P2RY1P2RY11ENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250255273-A1 AUTOMATED CANINE LINE-UP FOR DETECTION DOG RESEARCH TEXAS TECH UNIVERSITY SYSTEM 2025-08-14 US disclosed
US-20250215329-A1 METHOD AND SYSTEM FOR TREATING POLYMER WASTE COMPRISING HETEROATOMIC POLYMERS POINTBREAK AS (NO) 2025-07-03 US disclosed
US-12251861-B2 Barriers for plastic preforms and containers and preforms and containers made therewith PLASTIPAK BELGIUM BVBA (BE) 2025-03-18 US disclosed
WO-2025051753-A1 BLOWN FILM, METHOD OF PRODUCING IT, AND ARTICLES COMPRISING IT PERSTORP AB (SE) 2025-03-13 WO disclosed
US-20250064933-A1 CHIMERIC ANTIGEN RECEPTORS COMPRISING A PDZ BINDING MOTIF ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) 2025-02-27 US disclosed
EP-4427907-A2 BARRIERS FOR PLASTIC PREFORMS AND CONTAINERS, AND PREFORMS AND CONTAINERS MADE THEREWITH Plastipak Belgium BVBA (BE) 2024-09-11 EP disclosed
EP-3927516-B1 BARRIERS FOR INJECTION MOLDED PLASTIC PREFORMS OR CONTAINERS AND INJECTION MOLDED PLASTIC PREFORMS OR CONTAINERS MADE THEREWITH PLASTIPAK BELGIUM BVBA (BE) 2024-07-03 EP disclosed
WO-2024077230-A2 AUTOMATED CANINE LINE-UP FOR DETECTION DOG RESEARCH TEXAS TECH UNIVERSITY SYSTEM (US) 2024-04-11 WO disclosed
EP-3733171-B1 COMPOSITIONS COMPRISING HMB AND ATP AS WELL AS THEIR USE METABOLIC TECH LLC (US) 2023-10-25 EP disclosed
EP-4238559-A1 COMBINATIONS OF ACETAMINOPHEN AND N-ACETYL CYSTEINE FOR THE TREATMENT OF PAIN AND FEVER Centre Hospitalier Universitaire de Caen Normandie (FR) 2023-09-06 EP disclosed
CN-116600660-A Compositions and methods of use of beta-hydroxy-beta-methylbutyric acid (HMB) to improve muscle mass, strength, and muscle function without exercise 代谢科技有限责任公司 2023-08-15 CN disclosed
CN-116535855-A High heat-resistant transparent soluble polyimide film and preparation method and application thereof 福州大学 2023-08-04 CN disclosed
CN-110741242-B Ratio fluorescence imaging method 艾维拉斯生物科学公司 2023-07-07 CN disclosed
CN-116199946-A Ultra-high hardness rubber composite material with shape memory function and preparation method and application thereof 北京化工大学 2023-06-02 CN disclosed
US-20230149426-A1 Nutritional Intervention for Improving Muscular Function and Strength METABOLIC TECH LLC (US) 2023-05-18 US disclosed
EP-4167761-A1 COMPOSITIONS AND METHODS OF USE OF ?ETA-HYDROXY-?ETA-METHYLBUTYRATE (HMB) FOR IMPROVING MUSCLE MASS, STRENGTH AND MUSCULAR FUNCTION WITHOUT EXERCISE Metabolic Technologies, LLC (US) 2023-04-26 EP disclosed
US-11547713-B2 Nutritional intervention for improving muscular function and strength Metabolic Technologies, LLC (US) 2023-01-10 US disclosed
US-11369624-B2 Salts of prodrugs of piperazine and substituted piperidine antiviral agents VIIV HEALTHCARE UK (NO. 4) LIMITED 2022-06-28 US disclosed
US-20220161470-A1 BARRIERS FOR PLASTIC PREFORMS AND CONTAINERS AND PREFORMS AND CONTAINERS MADE THEREWITH PLASTIPAK BELGIUM BVBA (BE) 2022-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11369624-B2 Salts of prodrugs of piperazine and substituted piperidine antiviral agents CCR5, ZC3HAV1L, CCRL2 P2RX3 576/4885P2RY12 698/4885P2RY1 355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.