Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL9017530 | 0.89 | KDM4E (0.53) | KDM4EHPGDDNM1LMNAPAOX | |
| Acetic Acid SCHEMBL9438497 | 0.89 | KDM4E (0.53) | KDM4EHPGDDNM1LMNAPAOX | |
| SCHEMBL21954 | 0.88 | KDM4E (0.56) | KDM4EHPGDDNM1LMNAPAOX | |
| Methacrylic Acid SCHEMBL452014 | 0.87 | KDM4E (0.51) | KDM4EHPGDDNM1LMNAPAOX | |
| Ammonia Solution, Strong SCHEMBL23532663 | 0.87 | KDM4E (0.54) | KDM4EHPGDDNM1LMNAPAOX | |
| Hydrochloric Acid SCHEMBL111099 | 0.87 | KDM4E (0.54) | KDM4EHPGDDNM1LMNAPAOX | |
| Acetone SCHEMBL28357455 | 0.87 | KDM4E (0.54) | KDM4EHPGDDNM1LMNAPAOX | |
| Lactic Acid SCHEMBL7630264 | 0.85 | TGFBR1 (0.43) | KDM4ETGFBR1TP53POLBMEN1 | |
| Chloromethane SCHEMBL1655207 | 0.85 | KDM4E (0.53) | KDM4EHPGDDNM1LMNAPAOX | |
| SCHEMBL5052709 | 0.85 | KDM4E (0.53) | KDM4EHPGDDNM1LMNAPAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612388-A | Polyfunctional cationic monomer and process for producing the same | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-03-18 | — | — | US | disclosed |