Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 19/20 | 0.61 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.45 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9545804 | 0.83 | LTB4R (0.70) | LTB4RCYSLTR2CYSLTR1 | |
| SCHEMBL9545799 | 0.83 | LTB4R (0.70) | LTB4RCYSLTR2CYSLTR1 | |
| SCHEMBL8699763 | 0.80 | LTB4R (0.61) | LTB4R | |
| SCHEMBL8699765 | 0.80 | LTB4R (0.61) | LTB4R | |
| SCHEMBL8862059 | 0.79 | LTB4R (0.82) | LTB4R | |
| SCHEMBL8080164 | 0.79 | LTB4R (0.84) | LTB4R | |
| SCHEMBL8862108 | 0.79 | LTB4R (0.70) | LTB4R | |
| SCHEMBL9545824 | 0.79 | LTB4R (0.81) | LTB4R | |
| SCHEMBL8696845 | 0.79 | LTB4R (0.47) | LTB4R | |
| SCHEMBL8695142 | 0.79 | S1PR4 (0.48) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656636-A | TREATING PSORIASIS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-08-12 | — | — | US | disclosed |
| US-5633258-A | Pyridine compounds for treating leukotriene-related diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |
| US-5631262-A | Pyridine compounds for treating leukotriene-related diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-20 | — | — | US | disclosed |
| EP-0604529-A1 | PYRIDINE COMPOUNDS FOR TREATING LEUKOTRIENE-RELATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-06 | — | — | EP | disclosed |
| WO-1993006085-A1 | PYRIDINE COMPOUNDS FOR TREATING LEUKOTRIENE-RELATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-04-01 | — | — | WO | disclosed |