Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 19/20 | 0.81 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9545804 | 0.91 | LTB4R (0.70) | LTB4R | |
| SCHEMBL8078502 | 0.90 | LTB4R (1.00) | LTB4R | |
| SCHEMBL8078837 | 0.89 | LTB4R (1.00) | LTB4R | |
| SCHEMBL9545799 | 0.87 | LTB4R (0.70) | LTB4R | |
| SCHEMBL8080164 | 0.81 | LTB4R (0.84) | LTB4R | |
| SCHEMBL8862059 | 0.80 | LTB4R (0.82) | LTB4R | |
| SCHEMBL8825091 | 0.80 | LTB4R (0.60) | LTB4RDRD3LTB4R2 | |
| SCHEMBL8825095 | 0.80 | LTB4R (0.60) | LTB4RDRD3LTB4R2 | |
| SCHEMBL9545867 | 0.79 | LTB4R (0.60) | LTB4R | |
| SCHEMBL8862080 | 0.79 | LTB4R (0.61) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993022285-A1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-11-11 | — | — | WO | claimed |