Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27827515 | 0.82 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL825343 | 0.81 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2POLBNPC1LMNA | |
| SCHEMBL8863111 | 0.81 | NPSR1 (0.55) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL7876150 | 0.77 | MAPT (0.56) | MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL5280595 | 0.71 | SLC1A2 (0.54) | ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL7994479 | 0.69 | MAPT (0.46) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL7876180 | 0.69 | MEN1 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL3363210 | 0.69 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL3364793 | 0.66 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL25663640 | 0.65 | HPGD (0.50) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284780-B1 | PREVENT TUMOR NECROSIS FACTOR RETROVIRUS REPRODUCTION | CELGENE CORPORATION | 2001-09-04 | — | — | US | disclosed |
| EP-0800505-A1 | NOVEL IMMUNOTHERAPEUTIC ARYL AMIDES | CELGENE CORPORATION (US) | 1997-10-15 | — | — | EP | disclosed |
| WO-1996020915-A1 | NOVEL IMMUNOTHERAPEUTIC ARYL AMIDES | CELGENE CORPORATION (US) | 1996-07-11 | — | — | WO | disclosed |