Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of 2-Allylphenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Allylphenol SCHEMBL5488913 | 0.95 | GABRA1 (0.45) | GABRA1GABRB2ALDH1A1KDM4EPOLB | |
| 2-Allylphenol SCHEMBL18259392 | 0.95 | GABRA1 (0.45) | GABRA1GABRB2ALDH1A1KDM4EPOLB | |
| 2-Allylphenol SCHEMBL7187336 | 0.95 | GABRA1 (0.45) | GABRA1GABRB2ALDH1A1KDM4EPOLB | |
| 2-Allylphenol SCHEMBL1011363 | 0.95 | GABRA1 (0.45) | GABRA1GABRB2ALDH1A1KDM4EPOLB | |
| 2-Allylphenol SCHEMBL4348728 | 0.95 | GABRA1 (0.45) | GABRA1GABRB2ALDH1A1KDM4EPOLB | |
| 2-Allylphenol SCHEMBL11043591 | 0.95 | GABRA1 (0.45) | GABRA1GABRB2ALDH1A1KDM4EPOLB | |
| 2-Allylphenol SCHEMBL9297407 | 0.95 | GABRA1 (0.45) | GABRA1GABRB2ALDH1A1KDM4EPOLB | |
| 2-Allylphenol SCHEMBL5489315 | 0.95 | GABRA1 (0.45) | GABRA1GABRB2ALDH1A1KDM4EPOLB | |
| 2-Allylphenol SCHEMBL11501162 | 0.93 | GABRA1 (0.44) | GABRA1GABRB2ALDH1A1KDM4EPOLB | |
| 2-Allylphenol SCHEMBL9603869 | 0.86 | GABRA1 (0.43) | GABRA1GABRB2ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118222345-A | Low ash lubricating composition for controlling steel corrosion | 雅富顿化学公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-118165780-A | Driveline and transmission fluids for low speed wear and scuffing | 雅富顿化学公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-117946797-A | Lubricating composition for reducing wear of low temperature valve train | 雅富顿化学公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-117736788-A | Lubricating composition for fuel efficient motorcycle applications | 雅富顿化学公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-117487606-A | Detergent system for improving piston cleanliness | 雅富顿化学公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-117402663-A | Molybdenum-containing transmission lubricant | 雅富顿化学公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-117402667-A | Detergent system for oxidation resistance in lubricants | 雅富顿化学公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-117128110-A | Engine oil formulation for controlling particulate emissions | 雅富顿化学公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-115052959-B | Silicone functionalized viscosity index improver | 雅富顿化学公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-116891772-A | Durable magnet wire and lubricating fluid for electric and hybrid vehicle applications | 雅富顿化学公司 | 2023-10-17 | — | — | CN | disclosed |
| CN-115678645-A | Engine oil formulation for low timing chain stretching | 雅富顿化学公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-113597464-B | Lubricating composition for diesel particulate filter performance | 雅富顿化学公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-111040826-B | Lubricating oil composition and preparation method thereof | 中国石油化工股份有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-113597464-A | Lubricating composition for diesel particulate filter performance | 雅富顿化学公司 | 2021-11-02 | — | — | CN | disclosed |
| CN-107267259-B | Lubricant additives and lubricant compositions having improved friction characteristics | 雅富顿化学公司 | 2021-02-12 | — | — | CN | disclosed |
| CN-107267255-B | Lubricant additives and lubricant compositions having improved friction characteristics | 雅富顿化学公司 | 2021-01-29 | — | — | CN | disclosed |
| CN-111040842-A | Diesel engine oil composition and preparation method thereof | 中国石油化工股份有限公司 | 2020-04-21 | — | — | CN | disclosed |
| CN-111040826-A | Lubricating oil composition and preparation method thereof | 中国石油化工股份有限公司 | 2020-04-21 | — | — | CN | disclosed |
| CN-107400547-B | Synergistic dispersants | 雅富顿化学公司 | 2020-03-03 | — | — | CN | disclosed |
| US-5652201-A | INCLUDING OIL-SOLUBLE OVERBASED ALKALINE EARTH METAL-CONTAINING SULFONATE DETERGENT, BORON-FREE ADDITIVE FORMED BY HEATING ASHLESS DISPERSANT CONTAINING BASIC NITROGEN AND/OR HYDROXYL GROUP WITH INORGANIC PHOSPHORUS ACID | ETHYL PETROLEUM ADDITIVES INC. (US) | 1997-07-29 | — | — | US | disclosed |