Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of 2-Allylphenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 known ✓ | P14867 | 2/20 | 0.45 |
| ▸ | GABRB2 known ✓ | P47870 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Allylphenol SCHEMBL1011363 | 0.95 | GABRA1 (0.45) | GABRA1GABRB2ALDH1A1KDM4EPOLB | |
| 2-Allylphenol SCHEMBL8863113 | 0.95 | GABRA1 (0.45) | GABRA1GABRB2ALDH1A1KDM4EPOLB | |
| 2-Allylphenol SCHEMBL7187336 | 0.95 | GABRA1 (0.45) | GABRA1GABRB2ALDH1A1KDM4EPOLB | |
| 2-Allylphenol SCHEMBL5488913 | 0.95 | GABRA1 (0.45) | GABRA1GABRB2ALDH1A1KDM4EPOLB | |
| 2-Allylphenol SCHEMBL4348728 | 0.95 | GABRA1 (0.45) | GABRA1GABRB2ALDH1A1KDM4EPOLB | |
| 2-Allylphenol SCHEMBL18259392 | 0.95 | GABRA1 (0.45) | GABRA1GABRB2ALDH1A1KDM4EPOLB | |
| 2-Allylphenol SCHEMBL11043591 | 0.95 | GABRA1 (0.45) | GABRA1GABRB2ALDH1A1KDM4EPOLB | |
| 2-Allylphenol SCHEMBL9297407 | 0.95 | GABRA1 (0.45) | GABRA1GABRB2ALDH1A1KDM4EPOLB | |
| 2-Allylphenol SCHEMBL11501162 | 0.93 | GABRA1 (0.44) | GABRA1GABRB2ALDH1A1KDM4EPOLB | |
| 2-Allylphenol SCHEMBL9603869 | 0.86 | GABRA1 (0.43) | GABRA1GABRB2ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103298914-B | hydrocarbon treatment process | MERICHEM CO. (US) | 2016-05-25 | — | — | CN | claimed |
| CN-102482589-B | A method and a solution for treating hydrocarbon containing mercaptans | MERICHEM CO | 2015-05-20 | — | — | CN | claimed |
| CN-103298914-A | Hydrocarbon treatment process | MERICHEM CO | 2013-09-11 | — | — | CN | claimed |
| CN-102482589-A | Process and solution for treating mercaptan-containing hydrocarbons | MERICHEM CO | 2012-05-30 | — | — | CN | claimed |
| US-7252927-B2 | High performance curable polymers and processes for the preparation thereof | XEROX CORPORATION (US) | 2007-08-07 | — | — | US | claimed |
| EP-0370555-B1 | A process for the separation of a phenol | SHELL INT RESEARCH (NL) | 1994-09-07 | — | — | EP | claimed |
| CN-113511969-A | Preparation process of alkyl hydroxybenzoic acid | 新乡市瑞丰新材料股份有限公司 | 2021-10-19 | — | — | CN | disclosed |
| US-11040991-B2 | Allyl-phenoxy-cyclophosphazene compound, and production method therefor | OTSUKA CHEMICAL CO., LTD. (JP) | 2021-06-22 | — | — | US | disclosed |
| CN-107614509-B | Allylphenoxycyclophosphazene compound and method for producing same | 大塚化学株式会社 | 2020-05-12 | — | — | CN | disclosed |
| US-10435422-B2 | Allyl-phenoxy-cyclophosphazene compound, and production method therefor | OTSUKA CHEMICAL CO., LTD. (JP) | 2019-10-08 | — | — | US | disclosed |
| US-20180155376-A1 | ALLYL-PHENOXY-CYCLOPHOSPHAZENE COMPOUND, AND PRODUCTION METHOD THEREFOR | OTSUKA CHEMICAL CO., LTD. (JP) | 2018-06-07 | — | — | US | disclosed |
| CN-100413949-C | Lubricating oil composition containing an alkali metal salicylate detergent | CHEVRON ORONITE CO CHEVRON ORO (US) | 2008-08-27 | — | — | CN | disclosed |
| CN-100410355-C | Overbased detergents for lubricating oil compositions | CHEVRON ORONITE CO LTD (FR) | 2008-08-13 | — | — | CN | disclosed |
| EP-0972758-B1 | A process for producing phenolic compounds | MITSUBISHI GAS CHEMICAL CO (JP) | 2003-01-15 | — | — | EP | disclosed |
| EP-1209145-A2 | Process for preparing an aryl formate and an aromatic carboxylic acid | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-6187964-B1 | FORMING AN ARYL FORMATE AND AROMATIC CARBOXYLIC ACID BY OXIDATION AN AROMATIC ALDEHYDE WITH OXYGEN, SEPARATION A CARBOXYLIC ACID, ARYL FORMATE, UNREACTED ALDEHYDE MIXTURE AND DECOMPOSITION OF FORMATE TO PHENOL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0972758-A2 | A process for producing phenolic compounds | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2000-01-19 | — | — | EP | disclosed |
| US-4307078-A | Sulfonated bis(alkylphenoxy)alkanes as dental plaque barriers | JOHNSON & JOHNSON PRODUCTS INC. (US) | 1981-12-22 | — | — | US | disclosed |
| US-4124557-A | FLAME RETARDANTS, CYCLOPHOSPHAZENES, CURING | ARMSTRONG CORK COMPANY (US) | 1978-11-07 | — | — | US | disclosed |
| US-4107108-A | FOAMED FIRE-RETARDANT | ARMSTRONG CORK COMPANY (US) | 1978-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10435422-B2 | Allyl-phenoxy-cyclophosphazene compound, and production method therefor | CYP8B1, CYP1B1, CYP51A1 | GABRA1 555/4885GABRB2 770/4885ALDH1A1 141/4885 |
| US-20180155376-A1 | ALLYL-PHENOXY-CYCLOPHOSPHAZENE COMPOUND, AND PRODUCTION METHOD THEREFOR | CYP8B1, CYP1B1, CYP51A1 | GABRA1 555/4885GABRB2 770/4885ALDH1A1 141/4885 |
| US-11040991-B2 | Allyl-phenoxy-cyclophosphazene compound, and production method therefor | CYP8B1, CYP1B1, CYP51A1 | GABRA1 555/4885GABRB2 770/4885ALDH1A1 141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.