Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of 2-Allylphenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Allylphenol SCHEMBL11031219 | 0.92 | GABRA1 (0.38) | GABRA1GABRB2POLBKDM4EHTR1A | |
| 2-Allylphenol SCHEMBL11032407 | 0.92 | GABRA1 (0.38) | GABRA1GABRB2POLBKDM4EHTR1A | |
| 2-Allylphenol SCHEMBL7187336 | 0.90 | GABRA1 (0.45) | GABRA1GABRB2POLBKDM4EHTR1A | |
| 2-Allylphenol SCHEMBL5489315 | 0.86 | GABRA1 (0.45) | GABRA1GABRB2POLBKDM4EHTR1A | |
| 2-Allylphenol SCHEMBL1011363 | 0.86 | GABRA1 (0.45) | GABRA1GABRB2POLBKDM4EHTR1A | |
| 2-Allylphenol SCHEMBL9297407 | 0.86 | GABRA1 (0.45) | GABRA1GABRB2POLBKDM4EHTR1A | |
| 2-Allylphenol SCHEMBL5488913 | 0.86 | GABRA1 (0.45) | GABRA1GABRB2POLBKDM4EHTR1A | |
| 2-Allylphenol SCHEMBL4348728 | 0.86 | GABRA1 (0.45) | GABRA1GABRB2POLBKDM4EHTR1A | |
| 2-Allylphenol SCHEMBL18259392 | 0.86 | GABRA1 (0.45) | GABRA1GABRB2POLBKDM4EHTR1A | |
| 2-Allylphenol SCHEMBL8863113 | 0.86 | GABRA1 (0.45) | GABRA1GABRB2POLBKDM4EHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0047894-B2 | HOMOGENEOUS STORAGE-STABLE LIQUID BARIUM-CADMIUM-TRIPHOSPHITE STABILIZER SYSTEMS FOR POLYVINYL CHLORIDE RESINS | Argus Chemical Corporation (US) | 1990-09-05 | — | — | EP | claimed |
| US-4837257-A | Homogeneous storage-stable liquid barium-cadmium-triphosphite stabilizer systems for polyvinyl chloride resins | ARGUS CHEMICAL CORPORATION (US) | 1989-06-06 | — | — | US | claimed |
| US-4782170-A | Liquid polyvinyl chloride resin stabilizer systems based on complexes of organic triphosphites with zinc chloride | ARGUS CHEMICAL CORPORATION (US) | 1988-11-01 | — | — | US | claimed |
| EP-0047894-B1 | HOMOGENEOUS STORAGE-STABLE LIQUID BARIUM-CADMIUM-TRIPHOSPHITE STABILIZER SYSTEMS FOR POLYVINYL CHLORIDE RESINS | Argus Chemical Corporation (US) | 1985-11-13 | — | — | EP | claimed |
| US-4401779-A | Homogeneous liquid barium carbonate-barium alkyl phenate-cadmium carboxylate stabilizer systems for rigid polyvinyl chloride resins | ARGUS CHEMICAL CORPORATION (US) | 1983-08-30 | — | — | US | claimed |
| EP-0047894-A2 | Homogeneous storage-stable liquid barium-cadmium-triphosphite stabilizer systems for polyvinyl chloride resins | Argus Chemical Corporation (US) | 1982-03-24 | — | — | EP | claimed |
| EP-0292485-B1 | PROCESS FOR PREPARING HOMOGENEOUS STABILIZER COMPOSITIONS FOR VINYL HALIDE POLYMERS | The Lubrizol Corporation (US) | 1993-01-27 | — | — | EP | disclosed |
| EP-0047894-B2 | HOMOGENEOUS STORAGE-STABLE LIQUID BARIUM-CADMIUM-TRIPHOSPHITE STABILIZER SYSTEMS FOR POLYVINYL CHLORIDE RESINS | Argus Chemical Corporation (US) | 1990-09-05 | — | — | EP | disclosed |
| US-4837257-A | Homogeneous storage-stable liquid barium-cadmium-triphosphite stabilizer systems for polyvinyl chloride resins | ARGUS CHEMICAL CORPORATION (US) | 1989-06-06 | — | — | US | disclosed |
| US-4837257-A | Homogeneous storage-stable liquid barium-cadmium-triphosphite stabilizer systems for polyvinyl chloride resins | ARGUS CHEMICAL CORPORATION (US) | 1989-06-06 | — | — | US | disclosed |
| EP-0292485-A1 | PROCESS FOR PREPARING HOMOGENEOUS STABILIZER COMPOSITIONS FOR VINYL HALIDE POLYMERS. | LUBRIZOL CORP (US) | 1988-11-30 | — | — | EP | disclosed |
| US-4782170-A | Liquid polyvinyl chloride resin stabilizer systems based on complexes of organic triphosphites with zinc chloride | ARGUS CHEMICAL CORPORATION (US) | 1988-11-01 | — | — | US | disclosed |
| US-4760099-A | Polyol, halogenated organic blowing agent, amine catalyst organometallic compound, polyester polyol, surfactant, a-methylstyrene, polymethylene polyphenyleneisocyanate | SLOSS INDUSTRIES CORPORATION (US) | 1988-07-26 | — | — | US | disclosed |
| EP-0047894-B1 | HOMOGENEOUS STORAGE-STABLE LIQUID BARIUM-CADMIUM-TRIPHOSPHITE STABILIZER SYSTEMS FOR POLYVINYL CHLORIDE RESINS | Argus Chemical Corporation (US) | 1985-11-13 | — | — | EP | disclosed |
| US-4508863-A | WITH BRANCHED ALPHA-OLEFINS OLIGOMERS | ARGUS CHEMICAL CORPORATION (US) | 1985-04-02 | — | — | US | disclosed |
| US-4401779-A | Homogeneous liquid barium carbonate-barium alkyl phenate-cadmium carboxylate stabilizer systems for rigid polyvinyl chloride resins | ARGUS CHEMICAL CORPORATION (US) | 1983-08-30 | — | — | US | disclosed |
| US-4401779-A | Homogeneous liquid barium carbonate-barium alkyl phenate-cadmium carboxylate stabilizer systems for rigid polyvinyl chloride resins | ARGUS CHEMICAL CORPORATION (US) | 1983-08-30 | — | — | US | disclosed |
| EP-0047894-A2 | Homogeneous storage-stable liquid barium-cadmium-triphosphite stabilizer systems for polyvinyl chloride resins | Argus Chemical Corporation (US) | 1982-03-24 | — | — | EP | disclosed |
| EP-0047894-A2 | Homogeneous storage-stable liquid barium-cadmium-triphosphite stabilizer systems for polyvinyl chloride resins | Argus Chemical Corporation (US) | 1982-03-24 | — | — | EP | disclosed |
| US-4252698-A | A OVERBASED SULFONATE OR PHENOLATE, AND A 1,3-DIKETONE FOR VINYL CHLORIDE POLYMERS | ARGUS CHEMICAL CORPORATION (US) | 1981-02-24 | — | — | US | disclosed |