Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of 2-Allylphenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 known ✓ | P14867 | 2/20 | 0.45 |
| ▸ | GABRB2 known ✓ | P47870 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Allylphenol SCHEMBL27260576 | 0.98 | GABRA1 (0.44) | GABRA1GABRB2ALDH1A1KDM4EPOLB | |
| 2-Allylphenol SCHEMBL8863113 | 0.95 | GABRA1 (0.45) | GABRA1GABRB2ALDH1A1KDM4EPOLB | |
| 2-Allylphenol SCHEMBL7187336 | 0.95 | GABRA1 (0.45) | GABRA1GABRB2ALDH1A1KDM4EPOLB | |
| 2-Allylphenol SCHEMBL11043591 | 0.95 | GABRA1 (0.45) | GABRA1GABRB2ALDH1A1KDM4EPOLB | |
| 2-Allylphenol SCHEMBL5488913 | 0.95 | GABRA1 (0.45) | GABRA1GABRB2ALDH1A1KDM4EPOLB | |
| 2-Allylphenol SCHEMBL18259392 | 0.95 | GABRA1 (0.45) | GABRA1GABRB2ALDH1A1KDM4EPOLB | |
| 2-Allylphenol SCHEMBL5489315 | 0.95 | GABRA1 (0.45) | GABRA1GABRB2ALDH1A1KDM4EPOLB | |
| 2-Allylphenol SCHEMBL9297407 | 0.95 | GABRA1 (0.45) | GABRA1GABRB2ALDH1A1KDM4EPOLB | |
| 2-Allylphenol SCHEMBL1011363 | 0.95 | GABRA1 (0.45) | GABRA1GABRB2ALDH1A1KDM4EPOLB | |
| 2-Allylphenol SCHEMBL11501162 | 0.93 | GABRA1 (0.44) | GABRA1GABRB2ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430637-A | Synthesis method of tri (2-allylphenoxy) -triphenoxy cyclotriphosphazene | 西安近代化学研究所 | 2024-01-23 | — | — | CN | claimed |
| CN-113121922-A | Automobile instrument panel cladding part and preparation process thereof | 东莞井上建上汽车部件有限公司 | 2021-07-16 | — | — | CN | claimed |
| US-7252927-B2 | High performance curable polymers and processes for the preparation thereof | XEROX CORPORATION (US) | 2007-08-07 | — | — | US | claimed |
| EP-0162631-B1 | PREPARATION OF POLYPHOSPHAZENES AND THEIR USE | ETHYL CORPORATION (US) | 1990-03-21 | — | — | EP | claimed |
| US-4789728-A | EXTRACTING WITH LOWER ALCOHOL ALKALI METAL BASE SOLUTION | ETHYL CORPORATION (US) | 1988-12-06 | — | — | US | claimed |
| US-4665152-A | ALLYLPHENOXIDE COMPONENTS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1987-05-12 | — | — | US | claimed |
| EP-0215278-A1 | Curable poly(aryloxyphosphazene) copolymers | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1987-03-25 | — | — | EP | claimed |
| US-4576806-A | PHOSPHONITRILIC HALIDE, ALKALI METAL ALKOXIDE OR ARYLOXIDE, ALCOHOL SOLVENT | ETHYL CORPORATION (US) | 1986-03-18 | — | — | US | claimed |
| EP-0162631-A1 | Preparation of polyphosphazenes and their use | ETHYL CORPORATION (US) | 1985-11-27 | — | — | EP | claimed |
| US-4514550-A | Polyphosphazene process | ETHYL CORPORATION (US) | 1985-04-30 | — | — | US | claimed |
| CN-117430637-A | Synthesis method of tri (2-allylphenoxy) -triphenoxy cyclotriphosphazene | 西安近代化学研究所 | 2024-01-23 | — | — | CN | disclosed |
| CN-110564483-B | Lubricant compositions and dispersants having beneficial effect on oxidative stability | 雅富顿化学公司 | 2023-03-03 | — | — | CN | disclosed |
| CN-115678645-A | Engine oil formulation for low timing chain stretching | 雅富顿化学公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-113528220-B | Multifunctional branched polymers with improved low temperature properties | 雅富顿化学公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-110396450-B | Multifunctional branched polymers with improved low temperature properties | 雅富顿化学公司 | 2022-10-14 | — | — | CN | disclosed |
| EP-0215278-A1 | Curable poly(aryloxyphosphazene) copolymers | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1987-03-25 | — | — | EP | disclosed |
| EP-0194351-A1 | Aryloxy-alkoxy-alkenylphenoxy-substituted polyphosphazenes | ETHYL CORPORATION (US) | 1986-09-17 | — | — | EP | disclosed |
| US-4602048-A | Aryloxy-alkoxy-allylphenoxy substituted polyphosphazenes | ETHYL CORPORATION (US) | 1986-07-22 | — | — | US | disclosed |
| US-4576806-A | PHOSPHONITRILIC HALIDE, ALKALI METAL ALKOXIDE OR ARYLOXIDE, ALCOHOL SOLVENT | ETHYL CORPORATION (US) | 1986-03-18 | — | — | US | disclosed |
| US-3925511-A | Metallation of polymers and subsequent reaction to form modified or grafted polymers | UNIROYAL CHEMICAL COMPANY, INC. | 1975-12-09 | — | — | US | disclosed |