SCHEMBL8863544

SCHEMBL8863544

C=CCCC[Si](OCC)(OCC)OC(C)NCc1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.37
SIGMAR1 Q99720 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.34
TSHR P16473 1/20 0.34
ATM Q13315 1/20 0.34
CASR P41180 1/20 0.34
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MAPT P10636 1/20 0.33
POLB P06746 1/20 0.32
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31
FAAH O00519 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9860909 0.74 MAOA (0.41) SMN1; SMN2SIGMAR1MEN1KMT2AALDH1A1
SCHEMBL27946847 0.74 SIGMAR1 (0.45) SMN1; SMN2SIGMAR1L3MBTL1CASRMEN1
SCHEMBL15816499 0.72 SIGMAR1 (0.33) SMN1; SMN2SIGMAR1KMT2AALDH1A1FAAH
SCHEMBL29029448 0.71 CASR (0.43) SMN1; SMN2SIGMAR1L3MBTL1ATMCASR
SCHEMBL26100773 0.71 SMN1; SMN2 (0.38) SMN1; SMN2SIGMAR1L3MBTL1TSHRATM
SCHEMBL1519047 0.70 SIGMAR1 (0.35) SIGMAR1TSHRMEN1KMT2ACYP3A4
SCHEMBL16714867 0.69 SIGMAR1 (0.54) SMN1; SMN2SIGMAR1L3MBTL1ATMCASR
SCHEMBL154780 0.69 TSHR (0.44) TSHRALDH1A1
SCHEMBL16698562 0.67 ADH1B (0.40) SMN1; SMN2L3MBTL1TSHRMEN1KMT2A
Ethylene SCHEMBL27935498 0.67 MAOA (0.51) SIGMAR1MEN1KMT2AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5698627-A AN AQUEOUS SOLUTION OF A COPOLYMER OF AN ACRYLAMIDE, A VINYL COMPOUND HAVING A CATIONIC GROUP AND ANOTHER UNSATURATED COMPOUND PREPARED IN THE PRESENCE OF A POLYHYDROXY COMPOUND; FREENESS; RETENTION; HIGH STRENGTH JAPAN PMC CORPORATION (JP) 1997-12-16 US disclosed
EP-0735186-A2 Additive for papermaking and process for papermaking JAPAN PMC CORPORATION (JP) 1996-10-02 EP disclosed