Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 12/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 12/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27390069 | 1.00 | ATM (0.41) | ATML3MBTL1OPRD1OPRK1ITGA4 | |
| SCHEMBL27413418 | 0.82 | MMP1 (0.42) | ATML3MBTL1ITGA4ITGB7NPSR1 | |
| SCHEMBL948167 | 0.81 | L3MBTL1 (0.43) | ATML3MBTL1ITGA4ITGB7NPSR1 | |
| SCHEMBL948156 | 0.81 | L3MBTL1 (0.43) | ATML3MBTL1ITGA4ITGB7NPSR1 | |
| SCHEMBL7293819 | 0.81 | ITGA4 (0.44) | ATML3MBTL1ITGA4ITGB7NPSR1 | |
| SCHEMBL6593765 | 0.81 | ITGA4 (0.44) | ATML3MBTL1ITGA4ITGB7NPSR1 | |
| SCHEMBL6593761 | 0.81 | ITGA4 (0.44) | ATML3MBTL1ITGA4ITGB7NPSR1 | |
| SCHEMBL12450952 | 0.80 | CTSS (0.41) | ATML3MBTL1ITGA4ITGB7NPSR1 | |
| SCHEMBL6588963 | 0.76 | HPGD (0.48) | L3MBTL1NPSR1CTSSCTSLCTSB | |
| SCHEMBL6588969 | 0.76 | HPGD (0.48) | L3MBTL1NPSR1CTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672602-A | Substituted piperazine derivatives | HOECHST MARION ROUSSEL, INC. (US) | 1997-09-30 | — | — | US | disclosed |