Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865183 | 0.88 | HPGD (0.36) | PLK1CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL8864420 | 0.86 | ALDH1A1 (0.32) | PLK1CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL8864591 | 0.74 | MAPT (0.32) | PLK1CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL27582701 | 0.63 | NPC1 (0.61) | PKMALDH1A1RAB9AKDM4EMEN1 | |
| SCHEMBL6326547 | 0.62 | ALDH1A1 (0.42) | ALDH1A1RAB9AKDM4EMAPTKMT2A | |
| SCHEMBL6317044 | 0.61 | EDNRA (0.47) | ALDH1A1RAB9AKDM4EMAPTKMT2A | |
| SCHEMBL6317160 | 0.61 | EDNRA (0.47) | ALDH1A1RAB9AKDM4EMAPTKMT2A | |
| SCHEMBL6317175 | 0.61 | EDNRA (0.47) | ALDH1A1RAB9AKDM4EMAPTKMT2A | |
| SCHEMBL6325205 | 0.61 | ITGB3 (0.47) | ALDH1A1KDM4EMAPTLMNAGAA | |
| SCHEMBL6324398 | 0.61 | ITGB3 (0.47) | ALDH1A1KDM4EMAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633239-A | CARDIOVASCULAR DISORDERS; HYPOGLYCEMIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-27 | — | — | US | disclosed |