Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8864447 | 0.88 | PLK1 (0.33) | HPGDLMNAKDM4ECYP2C9CYP2C19 | |
| SCHEMBL8864569 | 0.86 | HPGD (0.34) | HPGDTDP1LMNAKDM4ECYP2C9 | |
| SCHEMBL8864541 | 0.75 | HPGD (0.34) | HPGDTDP1LMNAKDM4ECYP2C9 | |
| SCHEMBL8864420 | 0.74 | ALDH1A1 (0.32) | HPGDLMNAKDM4ECYP2C9CYP2C19 | |
| SCHEMBL8864941 | 0.72 | TDP1 (0.33) | HPGDTDP1LMNAKDM4EP2RX2 | |
| SCHEMBL8864591 | 0.63 | MAPT (0.32) | CYP2C9CYP2C19PKMCYP1A2CYP3A4 | |
| SCHEMBL6326547 | 0.61 | ALDH1A1 (0.42) | HPGDKDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL6317160 | 0.57 | EDNRA (0.47) | HPGDLMNAKDM4EALDH1A1MAPT | |
| SCHEMBL6317044 | 0.57 | EDNRA (0.47) | HPGDLMNAKDM4EALDH1A1MAPT | |
| SCHEMBL6317175 | 0.57 | EDNRA (0.47) | HPGDLMNAKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633239-A | CARDIOVASCULAR DISORDERS; HYPOGLYCEMIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-27 | — | — | US | disclosed |