Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.30 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8864541 | 0.89 | HPGD (0.34) | MAPTMEN1ALDH1A1KMT2ARAB9A | |
| SCHEMBL8864420 | 0.76 | ALDH1A1 (0.32) | MAPTMEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL8864972 | 0.76 | TACR1 (0.30) | — | |
| SCHEMBL8864447 | 0.74 | PLK1 (0.33) | MAPTMEN1ALDH1A1KMT2APLK1 | |
| SCHEMBL8864569 | 0.65 | HPGD (0.34) | MAPTKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8864941 | 0.62 | TDP1 (0.33) | — | |
| SCHEMBL8338913 | 0.61 | SMN1; SMN2 (0.36) | MEN1ALDH1A1TSHRKMT2ACYP1A2 | |
| SCHEMBL27582701 | 0.60 | NPC1 (0.61) | MEN1ALDH1A1KMT2ARAB9APKM | |
| SCHEMBL12489242 | 0.59 | POLB (0.56) | MAPTMEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL19112883 | 0.59 | POLB (0.56) | MAPTMEN1ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633239-A | CARDIOVASCULAR DISORDERS; HYPOGLYCEMIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-27 | — | — | US | disclosed |