Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057853 | 0.83 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL8369415 | 0.82 | PTGS1 (0.46) | SRD5A1PTGS1ALOX5KDM4EMEN1 | |
| SCHEMBL8863932 | 0.80 | ALOX15 (0.33) | PTGS1ALOX5KDM4EPOLBLMNA | |
| SCHEMBL7519825 | 0.79 | KDM4E (0.34) | SRD5A1PTGS1ALOX5KDM4EMEN1 | |
| SCHEMBL8691188 | 0.78 | KDM4E (0.34) | SRD5A1PTGS1ALOX5KDM4EMEN1 | |
| SCHEMBL7520741 | 0.77 | KDM4E (0.39) | SRD5A1PTGS1ALOX5KDM4EMEN1 | |
| SCHEMBL9028002 | 0.74 | KDM4E (0.37) | SRD5A1PTGS1ALOX5KDM4EMEN1 | |
| SCHEMBL8368610 | 0.71 | TUBB4A (0.39) | PTGS1ALOX5LMNA | |
| SCHEMBL9027992 | 0.70 | KDM4E (0.36) | SRD5A1PTGS1ALOX5KDM4EMEN1 | |
| SCHEMBL8690464 | 0.70 | KDM4E (0.34) | SRD5A1PTGS1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5674876-A | ANTIPROLIFERATIVE,-CARCINOGENIC AND -TUMOR AGENTS; SKIN DISORDERS; FREE RADICAL SCAVENGERS | RESEARCH DEVELOPMENT FOUNDATION (US) | 1997-10-07 | — | — | US | disclosed |
| WO-1996022089-A1 | p-HETEROATOM-SUBSTITUTED PHENOLS AND USES THEREOF | RESEARCH DEVELOPMENT FOUNDATION (US) | 1996-07-25 | — | — | WO | disclosed |