Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8864569 | 0.74 | HPGD (0.34) | TDP1HPGDKDM4ELMNA | |
| SCHEMBL8864541 | 0.73 | HPGD (0.34) | TDP1HPGDKDM4ELMNAHDAC3 | |
| SCHEMBL8865183 | 0.72 | HPGD (0.36) | TDP1HPGDKDM4ELMNAP2RX2 | |
| SCHEMBL8864253 | 0.68 | SLC6A2 (0.32) | SLC6A4 | |
| SCHEMBL8865073 | 0.68 | SLC6A2 (0.32) | SLC6A4 | |
| SCHEMBL8864951 | 0.67 | SLC6A2 (0.33) | SLC6A4 | |
| SCHEMBL8864560 | 0.66 | MEN1 (0.34) | TDP1SLC6A4LMNAP2RX2 | |
| SCHEMBL8865100 | 0.64 | MAOB (0.34) | LMNAP2RX2 | |
| SCHEMBL8864438 | 0.63 | SLC6A2 (0.33) | SLC6A4LMNA | |
| SCHEMBL8864420 | 0.63 | ALDH1A1 (0.32) | HPGDKDM4ELMNAHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633239-A | CARDIOVASCULAR DISORDERS; HYPOGLYCEMIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-27 | — | — | US | disclosed |