Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | GUSB | P08236 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8864420 | 0.89 | ALDH1A1 (0.32) | HPGDKDM4ELMNACYP1A2CYP3A4 | |
| SCHEMBL8865183 | 0.86 | HPGD (0.36) | HPGDTDP1KDM4ELMNACYP1A2 | |
| SCHEMBL8864541 | 0.77 | HPGD (0.34) | HPGDTDP1KDM4ELMNACYP1A2 | |
| SCHEMBL8864447 | 0.74 | PLK1 (0.33) | HPGDKDM4ELMNACYP1A2CYP3A4 | |
| SCHEMBL8864941 | 0.74 | TDP1 (0.33) | HPGDTDP1KDM4ELMNA | |
| SCHEMBL8864591 | 0.65 | MAPT (0.32) | CYP1A2CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL27582701 | 0.55 | NPC1 (0.61) | HPGDKDM4EPKMKMT2AGAA | |
| SCHEMBL12177297 | 0.54 | HPGD (1.00) | HPGDLMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20496927 | 0.54 | ALDH1A1 (0.83) | TDP1KDM4ELMNAPKMKMT2A | |
| SCHEMBL6326547 | 0.54 | ALDH1A1 (0.42) | HPGDKDM4EKMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633239-A | CARDIOVASCULAR DISORDERS; HYPOGLYCEMIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-27 | — | — | US | disclosed |