Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GUSB | P08236 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8864438 | 0.90 | SLC6A2 (0.33) | ALDH1A1SMN1; SMN2LMNASLC6A2SLC6A4 | |
| SCHEMBL8864625 | 0.89 | SLC6A2 (0.34) | MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL8865100 | 0.86 | MAOB (0.34) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8864674 | 0.80 | MAOB (0.35) | ALDH1A1SMN1; SMN2LMNAL3MBTL1HSD11B1 | |
| SCHEMBL8864563 | 0.75 | KMT2A (0.37) | MEN1KMT2A | |
| SCHEMBL8334765 | 0.68 | HPGD (0.37) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL8864568 | 0.68 | LMNA (0.34) | MEN1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL8864401 | 0.66 | HSD11B1 (0.32) | HSD11B1 | |
| SCHEMBL8864419 | 0.66 | SIGMAR1 (0.38) | SLC6A2SLC6A4 | |
| SCHEMBL8864941 | 0.66 | TDP1 (0.33) | LMNASLC6A4TDP1P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633239-A | CARDIOVASCULAR DISORDERS; HYPOGLYCEMIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-27 | — | — | US | disclosed |