Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8864424 | 0.88 | CNR2 (0.35) | P2RX7LMNA | |
| SCHEMBL8865178 | 0.82 | — | — | |
| SCHEMBL8864570 | 0.82 | AKR1B10 (0.30) | — | |
| SCHEMBL8341129 | 0.80 | CNR2 (0.35) | P2RX7LMNA | |
| SCHEMBL8864629 | 0.79 | — | — | |
| SCHEMBL8864440 | 0.79 | — | — | |
| SCHEMBL8336013 | 0.79 | P2RX7 (0.31) | P2RX7 | |
| SCHEMBL8865201 | 0.79 | CNR2 (0.37) | P2RX7LMNA | |
| SCHEMBL8864646 | 0.78 | — | — | |
| SCHEMBL8864339 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633239-A | CARDIOVASCULAR DISORDERS; HYPOGLYCEMIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-27 | — | — | US | disclosed |