Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.36 |
| ▸ | EBP | Q15125 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7609559 | 0.91 | KDM1A (0.39) | KDM1AAKR1B1SIGMAR1SRD5A1 | |
| SCHEMBL768782 | 0.80 | AKR1B1 (0.40) | KDM1AAKR1B1SIGMAR1EBP | |
| SCHEMBL8865243 | 0.74 | TSHR (0.38) | KDM1AAKR1B1 | |
| SCHEMBL31111261 | 0.73 | AKR1B1 (0.34) | AKR1B1KMT2A | |
| SCHEMBL7107247 | 0.71 | SIGMAR1 (0.34) | KDM1AAKR1B1SIGMAR1 | |
| SCHEMBL8611699 | 0.70 | ADRA2A (0.34) | KMT2A | |
| SCHEMBL8616201 | 0.70 | KDM4E (0.39) | SIGMAR1 | |
| SCHEMBL13330632 | 0.68 | SIGMAR1 (0.43) | KDM1AMEN1KMT2ASIGMAR1 | |
| SCHEMBL578812 | 0.67 | KDM1A (0.59) | KDM1AAKR1B1MEN1KMT2ASIGMAR1 | |
| SCHEMBL29556050 | 0.67 | KDM1A (0.59) | KDM1AAKR1B1MEN1KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658938-A | HYPOTENSIVE AGENT, ANTIISCHMIC AGENTS | U C B S.A. (BE) | 1997-08-19 | — | — | US | disclosed |
| EP-0717037-A1 | Substituted 1H-imidazoles having alpha 2-agonistic and alpha 1-antagonistic activity | U C B, S.A. (BE) | 1996-06-19 | — | — | EP | disclosed |