SCHEMBL8865632

SCHEMBL8865632

CCCC(NC(=O)OC)OC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.36
HDAC7 Q8WUI4 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HDAC9 Q9UKV0 1/20 0.35
HDAC5 Q9UQL6 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
TAS1R3 Q7RTX0 6/20 0.35
TAS1R1 Q7RTX1 6/20 0.35
CTSK P43235 3/20 0.35
CHRM1 P11229 1/20 0.34
AKR1A1 P14550 1/20 0.34
CHRM3 P20309 1/20 0.34
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
ADRA1A P35348 1/20 0.34
HRH1 P35367 1/20 0.34
DRD3 P35462 1/20 0.34
SLC6A3 Q01959 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8865351 0.82 MMP1 (0.35) EPHX1CA1CA2CTSKTSHR
SCHEMBL11364745 0.81 CAD (0.37) HDAC7HDAC8HDAC6HDAC9HDAC5
SCHEMBL6006436 0.80 EPHX1 (0.32) EPHX1HDAC7HDAC8HDAC6HDAC9
SCHEMBL28279224 0.77 CTSK (0.41) EPHX1HDAC7HDAC8HDAC6HDAC9
SCHEMBL2847929 0.76 TSHR (0.45) HDAC7HDAC8HDAC6HDAC9HDAC5
SCHEMBL20860864 0.76 ALDH1A1 (0.45) HDAC7HDAC8HDAC6HDAC9HDAC5
SCHEMBL11982683 0.76 ALDH1A1 (0.44) EPHX1HDAC7HDAC8HDAC6HDAC9
SCHEMBL16240316 0.76 ZDHHC7 (0.38) EPHX1HDAC7HDAC8HDAC6HDAC9
SCHEMBL15961884 0.76 ALDH1A1 (0.44) EPHX1HDAC7HDAC8HDAC6HDAC9
SCHEMBL10389666 0.76 GAA (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5700946-A ONE STEP CATALYTIC DEHYDROGENATION PROCESS OF N-(1-ALKOXYALKYL) COMPOUND NIPPON SHOKUBAI CO., LTD. (JP) 1997-12-23 US disclosed