Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUV39H2 | Q9H5I1 | 9/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866917 | 0.91 | ITGB3 (0.49) | SUV39H2ITGB3ITGA2BCHRM4HTR2A | |
| SCHEMBL8866386 | 0.91 | SUV39H2 (0.39) | SUV39H2ITGB3ITGA2BCHRM4 | |
| SCHEMBL8866999 | 0.85 | KCNA5 (0.44) | SUV39H2CHRM4HRH3 | |
| SCHEMBL8867330 | 0.82 | SUV39H2 (0.44) | SUV39H2CHRM4 | |
| SCHEMBL8867044 | 0.81 | ITGB3 (0.48) | SUV39H2ITGB3ITGA2BCHRM4 | |
| SCHEMBL8866339 | 0.81 | SUV39H2 (0.43) | SUV39H2ITGB3ITGA2BCHRM4 | |
| SCHEMBL9235823 | 0.80 | SUV39H2 (0.44) | SUV39H2CHRM4 | |
| SCHEMBL8867456 | 0.78 | CHRM4 (0.46) | SUV39H2CHRM4 | |
| SCHEMBL8866087 | 0.76 | GFER (0.41) | ITGB3ITGA2BCHRM4 | |
| SCHEMBL8866816 | 0.76 | MKNK1 (0.42) | SUV39H2CHRM4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |
| EP-0668278-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1995-08-23 | — | — | EP | disclosed |