Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | CFD | P00746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | FYN | P06241 | 3/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.41 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867799 | 0.89 | ALDH1A1 (0.50) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL8866671 | 0.87 | GFER (0.48) | NR4A2CFDRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL8867530 | 0.79 | ADORA3 (0.43) | CFDRAB9ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL8866558 | 0.76 | SUV39H2 (0.47) | RAB9ASMN1; SMN2KDM4ENPC1GFER | |
| SCHEMBL8866633 | 0.75 | NR4A2 (0.43) | NR4A2RAB9ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL25878920 | 0.74 | KDM4E (0.67) | RAB9ASMN1; SMN2KDM4EMAPTNPC1 | |
| SCHEMBL20946386 | 0.74 | ALDH1A3 (0.63) | RAB9ASMN1; SMN2KDM4EMAPTNPC1 | |
| SCHEMBL9235389 | 0.74 | ALDH1A1 (0.53) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL9252196 | 0.74 | ALDH1A1 (0.56) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL8866636 | 0.73 | KDM4E (0.41) | CFDRAB9ASMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |
| EP-0668278-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1995-08-23 | — | — | EP | disclosed |