Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CFD | P00746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866558 | 0.90 | SUV39H2 (0.47) | GFERALDH1A1SMN1; SMN2HPGDMAPK1 | |
| SCHEMBL8866550 | 0.87 | NR4A2 (0.47) | GFERALDH1A1SMN1; SMN2HPGDMAPK1 | |
| Trifluoroacetic Acid SCHEMBL8866119 | 0.85 | S1PR1 (0.45) | S1PR1LOXL2CHRM4FFAR1SUV39H2 | |
| SCHEMBL8867530 | 0.80 | ADORA3 (0.43) | GFERALDH1A1SMN1; SMN2MAPK1CFD | |
| SCHEMBL8866401 | 0.77 | CHRM4 (0.46) | GFERALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL8867456 | 0.77 | CHRM4 (0.46) | GFERALDH1A1SMN1; SMN2HPGDMAPK1 | |
| SCHEMBL25878920 | 0.76 | KDM4E (0.67) | GFERALDH1A1SMN1; SMN2HPGDMAPK1 | |
| SCHEMBL8867134 | 0.76 | SUV39H2 (0.45) | GFERALDH1A1SMN1; SMN2HPGDMAPK1 | |
| Hydrochloric Acid SCHEMBL8866506 | 0.75 | CHRM4 (0.44) | GFERALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL8867799 | 0.75 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2KDM4ERAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |
| EP-0668278-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1995-08-23 | — | — | EP | disclosed |