Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 6/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866821 | 0.90 | WDR5 (0.45) | WDR5PDE10ADPP4DPP7 | |
| SCHEMBL8866516 | 0.85 | WDR5 (0.40) | WDR5CHEK1GPR119ACACBACACA | |
| SCHEMBL8866103 | 0.84 | NPC1 (0.39) | WDR5GPR119NPC1 | |
| SCHEMBL8866628 | 0.80 | GNA11 (0.37) | WDR5CHEK1GPR119ACACBACACA | |
| SCHEMBL8866724 | 0.77 | WDR5 (0.42) | WDR5PDE10A | |
| SCHEMBL8866085 | 0.76 | ACACB (0.54) | ACACBACACAKDM4E | |
| SCHEMBL8867025 | 0.76 | WDR5 (0.44) | WDR5DPP4DPP7 | |
| SCHEMBL8867053 | 0.71 | NPC1 (0.38) | WDR5GPR119NPC1 | |
| Trifluoroacetic Acid SCHEMBL8866836 | 0.71 | F11 (0.40) | WDR5CHEK1PDE10ANPC1LMNA | |
| SCHEMBL8867571 | 0.69 | ALDH1A1 (0.49) | KMT2ANPC1LMNARAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |