Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 15/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | LDHB | P07195 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.36 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.36 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.36 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866516 | 0.90 | WDR5 (0.40) | WDR5USP30DPP4DPP7 | |
| SCHEMBL8866821 | 0.86 | WDR5 (0.45) | WDR5LDHALDHBUSP30DPP4 | |
| SCHEMBL8866827 | 0.85 | WDR5 (0.41) | WDR5USP30 | |
| SCHEMBL8867021 | 0.78 | ACACB (0.50) | WDR5 | |
| SCHEMBL8867053 | 0.77 | NPC1 (0.38) | WDR5 | |
| SCHEMBL8866091 | 0.76 | WDR5 (0.40) | WDR5DPP4DPP7 | |
| SCHEMBL8866724 | 0.72 | WDR5 (0.42) | WDR5 | |
| SCHEMBL8866347 | 0.71 | RAB9A (0.46) | — | |
| SCHEMBL8866813 | 0.69 | ACACB (0.51) | WDR5 | |
| SCHEMBL8866424 | 0.69 | ALDH1A1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |