Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | SNCA | P37840 | 2/20 | 0.53 |
| ▸ | SMO | Q99835 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867756 | 0.90 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL8867760 | 0.90 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL8867294 | 0.86 | MAOB (0.53) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL8868501 | 0.81 | MEN1 (0.47) | RAB9AMEN1KMT2ASNCAALDH1A1 | |
| SCHEMBL8867685 | 0.80 | MAOB (0.46) | MEN1KMT2APKMSNCAMAPT | |
| SCHEMBL8867672 | 0.79 | PKM (0.55) | NPC1KMT2APKMSNCASIRT1 | |
| SCHEMBL8867677 | 0.79 | PKM (0.55) | NPC1KMT2APKMSNCASIRT1 | |
| SCHEMBL8867002 | 0.78 | PKM (0.54) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL8867045 | 0.78 | KCNK3 (0.59) | MEN1KMT2APKMSNCAMAPT | |
| SCHEMBL8866604 | 0.78 | L3MBTL1 (0.70) | NPC1RAB9AMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |