Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 7/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 8/20 | 0.55 |
| ▸ | RAB9A | P51151 | 8/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27110837 | 0.95 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1MAPK1HPGDTP53 | |
| SCHEMBL4237996 | 0.92 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1MAPK1HPGDTP53 | |
| SCHEMBL19399318 | 0.91 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1MAPK1HPGDTP53 | |
| SCHEMBL7562459 | 0.91 | SMN1; SMN2 (0.77) | SMN1; SMN2ALDH1A1MAPK1HPGDTP53 | |
| SCHEMBL1022959 | 0.90 | RAB9A (0.68) | SMN1; SMN2ALDH1A1MAPK1HPGDTP53 | |
| SCHEMBL12927962 | 0.90 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1MAPK1HPGDTP53 | |
| SCHEMBL7472487 | 0.90 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1MAPK1HPGDTP53 | |
| SCHEMBL984289 | 0.89 | RAB9A (0.62) | SMN1; SMN2ALDH1A1MAPK1HPGDTP53 | |
| SCHEMBL13387551 | 0.88 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1MAPK1HPGDTP53 | |
| SCHEMBL9211588 | 0.88 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1MAPK1HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9637445-B2 | Isocyanate production process using composition containing carbamic acid ester and aromatic hydroxy compound, and composition for transfer and storage of carbamic acid ester | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2017-05-02 | — | — | US | disclosed |
| EP-2147909-B1 | METHOD FOR PRODUCTION OF ISOCYANATE USING COMPOSITION COMPRISING CARBAMIC ACID ESTER AND AROMATIC HYDROXY COMPOUND, AND COMPOSITION FOR TRANSPORT OR STORAGE OF CARBAMIC ACID ESTER | ASAHI CHEMICAL IND (JP) | 2016-12-14 | — | — | EP | disclosed |
| US-9234067-B2 | Material forming supramolecular structures, process and uses | HENKEL AG & CO. KGAA (DE) | 2016-01-12 | — | — | US | disclosed |
| EP-1792925-B1 | Novel material forming supramolecular structures, process and uses | HENKEL AG & CO KGAA (DE) | 2015-10-07 | — | — | EP | disclosed |
| US-20150259279-A1 | Isocyanate Production Process Using Composition Containing Carbamic Acid Ester and Aromatic Hydroxy Compound, and Composition for Transfer and Storage of Carbamic Acid Ester | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2015-09-17 | — | — | US | disclosed |
| US-9056819-B2 | Isocyanate production process using composition containing carbamic acid ester and aromatic hydroxy compound, and composition for transfer and storage of carbamic acid ester | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2015-06-16 | — | — | US | disclosed |
| EP-2088138-B1 | Process for producing isocyanate | ASAHI KASEI CHEMICALS CORP (JP) | 2013-02-27 | — | — | EP | disclosed |
| US-8362293-B2 | Process for producing isocyanates | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2013-01-29 | — | — | US | disclosed |
| US-8053595-B2 | Process for producing isocyanates | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-11-08 | — | — | US | disclosed |
| EP-2088137-B1 | A PROCESS FOR PRODUCING ISOCYANATES | ASAHI KASEI CHEMICALS CORP (JP) | 2011-01-12 | — | — | EP | disclosed |
| US-20100069665-A1 | PROCESS FOR PRODUCING ISOCYANATES | AHAHI KASEI CHEMICALS CORPORATION (JP) | 2010-03-18 | — | — | US | disclosed |
| US-20100029981-A1 | PROCESS FOR PRODUCING ISOCYANATES | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2010-02-04 | — | — | US | disclosed |
| EP-2147909-A1 | METHOD FOR PRODUCTION OF ISOCYANATE USING COMPOSITION COMPRISING CARBAMIC ACID ESTER AND AROMATIC HYDROXY COMPOUND, AND COMPOSITION FOR TRANSPORT OR STORAGE OF CARBAMIC ACID ESTER | Asahi Kasei Chemicals Corporation (JP) | 2010-01-27 | — | — | EP | disclosed |
| US-20090291236-A1 | METHOD FOR PRODUCING SHAPE-ANISOTROPIC METAL PARTICLES, COLORING COMPOSITION, PHOTOSENSITIVE TRANSFER MATERIAL, SUBSTRATE WITH A BLACK IMAGE, COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT | FUJIFILM CORPORATION (JP) | 2009-11-26 | — | — | US | disclosed |
| US-20090291236-A1 | METHOD FOR PRODUCING SHAPE-ANISOTROPIC METAL PARTICLES, COLORING COMPOSITION, PHOTOSENSITIVE TRANSFER MATERIAL, SUBSTRATE WITH A BLACK IMAGE, COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT | FUJIFILM CORPORATION (JP) | 2009-11-26 | — | — | US | disclosed |
| EP-2088137-A1 | METHOD FOR PRODUCING ISOCYANATE | Asahi Kasei Chemicals Corporation (JP) | 2009-08-12 | — | — | EP | disclosed |
| EP-2088138-A1 | PROCESS FOR PRODUCING ISOCYANATE | Asahi Kasei Chemicals Corporation (JP) | 2009-08-12 | — | — | EP | disclosed |
| US-20080200718-A1 | Reacting (thio)isocyanate with amine, alcohol or thiol | HENKEL KGAA (DE) | 2008-08-21 | — | — | US | disclosed |
| EP-1792925-A1 | Novel material forming supramolecular structures, process and uses | National Starch and Chemical Investment Holding Corporation (US) | 2007-06-06 | — | — | EP | disclosed |
| US-4069240-A | GROUP 8 METAL CATALYST | UNIROYAL, INC. (US) | 1978-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029981-A1 | PROCESS FOR PRODUCING ISOCYANATES | PAH, ALKBH3, GRHPR | SMN1; SMN2 4580/4885ALDH1A1 906/4885MAPK1 2340/4885 |
| US-20100069665-A1 | PROCESS FOR PRODUCING ISOCYANATES | CPS1, IDH2, PHGDH | SMN1; SMN2 3651/4885ALDH1A1 1960/4885MAPK1 3838/4885 |
| US-20080200718-A1 | Reacting (thio)isocyanate with amine, alcohol or thiol | TST, CBR3, TBCB | SMN1; SMN2 2986/4885ALDH1A1 747/4885MAPK1 2651/4885 |
| US-20150259279-A1 | Isocyanate Production Process Using Composition Containing Carbamic Acid Ester and Aromatic Hydroxy Compound, and Composition for Transfer and Storage of Carbamic Acid Ester | PAH, APEH, CPS1 | SMN1; SMN2 4075/4885ALDH1A1 2908/4885MAPK1 3960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.