Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.65 |
| ▸ | THRB | P10828 | 2/20 | 0.65 |
| ▸ | TGM2 | P21980 | 15/20 | 0.58 |
| ▸ | F13A1 | P00488 | 5/20 | 0.58 |
| ▸ | TGM1 | P22735 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.58 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867209 | 0.86 | THRA (0.65) | THRATHRBTGM2F13A1TGM1 | |
| SCHEMBL16242100 | 0.85 | TGM2 (0.61) | THRATHRBTGM2F13A1TGM1 | |
| SCHEMBL12265208 | 0.84 | THRA (0.63) | THRATHRBTGM2F13A1TGM1 | |
| SCHEMBL12832351 | 0.84 | THRB (0.77) | THRATHRBTGM2F13A1TGM1 | |
| SCHEMBL440756 | 0.83 | TGM2 (0.63) | THRATHRBTGM2F13A1TGM1 | |
| SCHEMBL11511625 | 0.83 | THRA (0.61) | THRATHRBTGM2F13A1TGM1 | |
| SCHEMBL439369 | 0.82 | TGM2 (0.79) | THRATHRBTGM2F13A1TGM1 | |
| SCHEMBL1191835 | 0.81 | TGM2 (0.61) | THRATHRBTGM2F13A1TGM1 | |
| SCHEMBL6677167 | 0.81 | THRA (0.88) | THRATHRBTGM2F13A1TGM1 | |
| SCHEMBL27632061 | 0.81 | THRA (0.60) | THRATHRBTGM2F13A1TGM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |