Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.40 |
| ▸ | CDK2 | P24941 | 3/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867455 | 1.00 | KMT2A (0.50) | KMT2AMEN1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL8867470 | 0.91 | KMT2A (0.50) | KMT2AMEN1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL8868076 | 0.83 | NPC1 (0.58) | KMT2AMEN1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL8868083 | 0.83 | NPC1 (0.58) | KMT2AMEN1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL8867288 | 0.77 | MAOB (0.53) | KMT2AMEN1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL8867284 | 0.77 | MAOB (0.53) | KMT2AMEN1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL8867761 | 0.76 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1HTTLMNA | |
| SCHEMBL8867757 | 0.76 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1HTTLMNA | |
| SCHEMBL8867679 | 0.76 | MAOB (0.46) | KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8867682 | 0.76 | MAOB (0.46) | KMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |