Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31329309 | 0.89 | DGKA (0.54) | ALOX5NAAA | |
| SCHEMBL28577101 | 0.87 | ALOX5 (0.57) | ALOX5F2RL1ALDH1A1TDP1CALM1 | |
| SCHEMBL15164336 | 0.87 | ALOX5 (0.60) | ALOX5MAPTL3MBTL1RECQLKMT2A | |
| SCHEMBL28579204 | 0.84 | ALOX5 (0.57) | ALOX5L3MBTL1RECQLKMT2ALMNA | |
| SCHEMBL8867570 | 0.82 | TDP1 (0.62) | ALOX5MAPTKMT2ALMNAALDH1A1 | |
| SCHEMBL8867973 | 0.82 | TDP1 (0.62) | ALOX5MAPTKMT2ALMNAALDH1A1 | |
| SCHEMBL8868655 | 0.82 | TDP1 (0.62) | ALOX5MAPTKMT2ALMNAALDH1A1 | |
| SCHEMBL5833853 | 0.81 | ALDH1A1 (0.53) | MAPTL3MBTL1KMT2ALMNAALDH1A1 | |
| SCHEMBL1239542 | 0.81 | ALOX5 (0.65) | ALOX5MAPTL3MBTL1KMT2ALMNA | |
| SCHEMBL15164337 | 0.81 | ALOX5 (0.60) | ALOX5MAPTL3MBTL1RECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599966-A | SUITABLE FOR TREATMENT OF DISEASES OF RESPIRATORY PASSAGES | BYK NEDERLAND BV (NL) | 1997-02-04 | — | — | US | disclosed |
| EP-0664788-A1 | SUBSTITUTED ETHANOLAMINE ESTERS | Byk Nederland BV (NL) | 1995-08-02 | — | — | EP | disclosed |
| WO-1994008945-A1 | SUBSTITUTED ETHANOLAMINE ESTERS | BYK NEDERLAND BV (NL) | 1994-04-28 | — | — | WO | disclosed |