Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868289 | 0.82 | SMN1; SMN2 (0.57) | POLBAOC3TSHRNPC1RAB9A | |
| SCHEMBL14445095 | 0.80 | TSHR (0.37) | POLBHRH3THRATHRBAOC3 | |
| SCHEMBL13017226 | 0.79 | AOC3 (0.46) | POLBHRH3AOC3SPHK1NPC1 | |
| Bromide SCHEMBL7202745 | 0.79 | NOS3 (0.46) | POLBAOC3 | |
| SCHEMBL8867550 | 0.79 | POLB (0.46) | POLBHRH3THRATHRBAOC3 | |
| SCHEMBL8867408 | 0.78 | KMT2A (0.59) | HRH3AOC3TSHRNPC1RAB9A | |
| SCHEMBL10668375 | 0.78 | TSHR (0.38) | POLBHRH3THRATHRBSPHK1 | |
| SCHEMBL10668382 | 0.78 | SRC (0.52) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8866580 | 0.77 | RXFP1 (0.56) | POLBHRH3THRATHRBAOC3 | |
| SCHEMBL7877522 | 0.76 | LOXL2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |