Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | NPC1 | O15118 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 1.00 |
| ▸ | HK1 | P19367 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | GALK1 | P51570 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 1.00 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 1.00 |
| ▸ | AHR | P35869 | 1/20 | 0.56 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29453856 | 1.00 | KMT2A (1.00) | KMT2AMAPTMEN1NPC1KDM4E | |
| Fluorene SCHEMBL28370298 | 0.90 | NPC1 (0.81) | KMT2AMAPTMEN1NPC1KDM4E | |
| Acridan SCHEMBL20594012 | 0.79 | MAPT (0.65) | KMT2AMAPTMEN1NPC1KDM4E | |
| Acridan SCHEMBL29446489 | 0.79 | MAPT (0.65) | KMT2AMAPTMEN1NPC1KDM4E | |
| Acridan SCHEMBL183367 | 0.79 | MAPT (0.65) | KMT2AMAPTMEN1NPC1KDM4E | |
| Acridan SCHEMBL29405807 | 0.79 | MAPT (0.65) | KMT2AMAPTMEN1NPC1KDM4E | |
| SCHEMBL88725 | 0.79 | MEN1 (0.65) | KMT2AMAPTMEN1NPC1KDM4E | |
| SCHEMBL4571016 | 0.77 | MAPT (0.62) | KMT2AMAPTMEN1NPC1KDM4E | |
| Acridan SCHEMBL15412652 | 0.77 | MAPT (0.62) | KMT2AMAPTMEN1NPC1KDM4E | |
| Acridan SCHEMBL10813635 | 0.77 | MAPT (0.62) | KMT2AMAPTMEN1NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115813915-B | Application of polysubstituted indoline-2-thioketone compound in preparation of medicine for treating non-alcoholic fatty liver and diabetes | 华东师范大学 | 2025-02-11 | — | — | CN | claimed |
| CN-115813915-A | Application of polysubstituted indoline-2-thioketone compound in preparation of drugs for treating non-alcoholic fatty liver and diabetes | 华东师范大学 | 2023-03-21 | — | — | CN | claimed |
| CN-113234007-B | Synthesis method of 4-indolylthiobutanoic acid derivative | 四川轻化工大学 | 2022-10-25 | — | — | CN | claimed |
| CN-113234007-A | Synthesis method of 4-indolylthiobutyric acid derivative | 四川轻化工大学 | 2021-08-10 | — | — | CN | claimed |
| US-8609712-B2 | Purification of progesterone receptor modulators | WYETH LLC (US) | 2013-12-17 | — | — | US | claimed |
| US-20130012702-A1 | PURIFICATION OF PROGESTERONE RECEPTOR MODULATORS | WYETH LLC (US) | 2013-01-10 | — | — | US | claimed |
| US-8309594-B2 | Purification of progesterone receptor modulators | WYETH LLC (US) | 2012-11-13 | — | — | US | claimed |
| US-20090143577-A1 | PURIFICATION OF PROGESTERONE RECEPTOR MODULATORS | WYETH (US) | 2009-06-04 | — | — | US | claimed |
| US-7514466-B2 | Purification of progesterone receptor modulators | WYETH (US) | 2009-04-07 | — | — | US | claimed |
| EP-1756072-A2 | PURIFICATION OF PROGESTERONE RECEPTOR MODULATORS | Wyeth (US) | 2007-02-28 | — | — | EP | claimed |
| WO-2005104711-A2 | PURIFICATION OF PROGESTERONE RECEPTOR MODULATORS | WYETH (US) | 2005-11-10 | — | — | WO | claimed |
| US-20050250766-A1 | Purification of progesterone receptor modulators | WYETH (US) | 2005-11-10 | — | — | US | claimed |
| US-5556874-A | ENZYME INHIBITORS AS ANTICARCINOGENIC AGENTS | WARNER LAMBERT COMPANY (US) | 1996-09-17 | — | — | US | claimed |
| JP-H08503450-A | — | — | 1996-04-16 | — | — | JP | claimed |
| EP-0654024-A1 | 2-THIOINDOLES (SELENOINDOLES) AND RELATED DISULFIDES (SELENIDES) WHICH INHIBIT PROTEIN TYROSINE KINASES AND WHICH HAVE ANTITUMOR PROPERTIES | WARNER-LAMBERT COMPANY (US) | 1995-05-24 | — | — | EP | claimed |
| WO-1994003427-A1 | 2-THIOINDOLES (SELENOINDOLES) AND RELATED DISULFIDES (SELENIDES) WHICH INHIBIT PROTEIN TYROSINE KINASES AND WHICH HAVE ANTITUMOR PROPERTIES | WARNER-LAMBERT COMPANY (US) | 1994-02-17 | — | — | WO | claimed |
| JP-55007201-A | — | — | None | — | — | JP | disclosed |
| CN-120172991-A | Preparation method of thiopyrano [2,3-b ] indole compounds | 深圳职业技术大学 | 2025-06-20 | — | — | CN | disclosed |
| US-4080207-A | Radiation-sensitive compositions and photographic elements containing N-(acylhydrazinophenyl) thioamide nucleating agents | EASTMAN KODAK COMPANY (US) | 1978-03-21 | — | — | US | disclosed |
| US-4059583-A | CARDIAC RATE LOWERING | MCNEIL LABORATORIES, INCORPORATED (US) | 1977-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012702-A1 | PURIFICATION OF PROGESTERONE RECEPTOR MODULATORS | PGR, PGRMC1, GNRHR | KMT2A 2999/4885MAPT 4392/4885MEN1 2490/4885 |
| US-20090143577-A1 | PURIFICATION OF PROGESTERONE RECEPTOR MODULATORS | PGR, PGRMC1, GNRHR | KMT2A 2999/4885MAPT 4392/4885MEN1 2490/4885 |
| US-20050250766-A1 | Purification of progesterone receptor modulators | PGR, PGRMC1, PGRMC2 | KMT2A 3043/4885MAPT 4433/4885MEN1 2239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.