Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.81 |
| ▸ | MAPT | P10636 | 2/20 | 0.81 |
| ▸ | RAB9A | P51151 | 2/20 | 0.81 |
| ▸ | MEN1 | O00255 | 2/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.81 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.81 |
| ▸ | THRB | P10828 | 1/20 | 0.81 |
| ▸ | HK1 | P19367 | 1/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.81 |
| ▸ | RECQL | P46063 | 1/20 | 0.81 |
| ▸ | GALK1 | P51570 | 1/20 | 0.81 |
| ▸ | BLM | P54132 | 1/20 | 0.81 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.81 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL88685 | 0.90 | KMT2A (1.00) | NPC1KDM4EMAPTRAB9AMEN1 | |
| SCHEMBL29453856 | 0.90 | KMT2A (1.00) | NPC1KDM4EMAPTRAB9AMEN1 | |
| Fluorene SCHEMBL28396879 | 0.77 | AHR (0.81) | NPC1KDM4EMAPTRAB9AMEN1 | |
| Acridan SCHEMBL183367 | 0.76 | MAPT (0.65) | NPC1KDM4EMAPTRAB9AMEN1 | |
| Acridan SCHEMBL29446489 | 0.76 | MAPT (0.65) | NPC1KDM4EMAPTRAB9AMEN1 | |
| Acridan SCHEMBL29405807 | 0.76 | MAPT (0.65) | NPC1KDM4EMAPTRAB9AMEN1 | |
| Acridan SCHEMBL20594012 | 0.76 | MAPT (0.65) | NPC1KDM4EMAPTRAB9AMEN1 | |
| SCHEMBL18904613 | 0.74 | NPC1 (0.48) | NPC1KDM4EMAPTRAB9AMEN1 | |
| SCHEMBL2087698 | 0.74 | TDP2 (0.66) | NPC1KDM4EMAPTRAB9AMEN1 | |
| Acridan SCHEMBL15412652 | 0.74 | MAPT (0.62) | NPC1KDM4EMAPTRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110790771-B | Micromolecular material based on bisthiooxindole fluorene unit and preparation method and application thereof | 华南理工大学 | 2022-09-20 | — | — | CN | claimed |
| CN-107540822-B | Conjugated polymer luminescent material based on bisthiooxindole fluorene unit and preparation method and application thereof | 华南理工大学 | 2020-09-22 | — | — | CN | claimed |
| CN-110790771-A | Micromolecular material based on bisthiooxindole fluorene unit and preparation method and application thereof | 华南理工大学 | 2020-02-14 | — | — | CN | claimed |
| CN-110790742-B | Small-molecule luminescent material based on naphtho-sulfur-oxygen-fluorene unit and preparation method and application thereof | 华南理工大学 | 2023-02-14 | — | — | CN | disclosed |
| CN-110790771-B | Micromolecular material based on bisthiooxindole fluorene unit and preparation method and application thereof | 华南理工大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-110790771-B | Micromolecular material based on bisthiooxindole fluorene unit and preparation method and application thereof | 华南理工大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-110790771-B | Micromolecular material based on bisthiooxindole fluorene unit and preparation method and application thereof | 华南理工大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-107540822-B | Conjugated polymer luminescent material based on bisthiooxindole fluorene unit and preparation method and application thereof | 华南理工大学 | 2020-09-22 | — | — | CN | disclosed |
| CN-107540822-B | Conjugated polymer luminescent material based on bisthiooxindole fluorene unit and preparation method and application thereof | 华南理工大学 | 2020-09-22 | — | — | CN | disclosed |
| CN-107540822-B | Conjugated polymer luminescent material based on bisthiooxindole fluorene unit and preparation method and application thereof | 华南理工大学 | 2020-09-22 | — | — | CN | disclosed |
| CN-110790771-A | Micromolecular material based on bisthiooxindole fluorene unit and preparation method and application thereof | 华南理工大学 | 2020-02-14 | — | — | CN | disclosed |
| CN-110790771-A | Micromolecular material based on bisthiooxindole fluorene unit and preparation method and application thereof | 华南理工大学 | 2020-02-14 | — | — | CN | disclosed |
| CN-110790771-A | Micromolecular material based on bisthiooxindole fluorene unit and preparation method and application thereof | 华南理工大学 | 2020-02-14 | — | — | CN | disclosed |
| CN-110790742-A | Small-molecule luminescent material based on naphtho-sulfur-oxygen-fluorene unit and preparation method and application thereof | 华南理工大学 | 2020-02-14 | — | — | CN | disclosed |