Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.61 |
| ▸ | CA2 | P00918 | 7/20 | 0.61 |
| ▸ | CA9 | Q16790 | 5/20 | 0.61 |
| ▸ | CA12 | O43570 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NSD2 | O96028 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870068 | 0.84 | CA2 (0.56) | CA1CA2CA9CA12KMT2A | |
| SCHEMBL22460148 | 0.82 | CYP1A2 (0.59) | CA1CA2CA9MEN1KMT2A | |
| SCHEMBL680127 | 0.81 | CA12 (0.56) | CA1CA2CA9CA12NSD2 | |
| SCHEMBL8870101 | 0.78 | GUSB (0.48) | CA1CA2CA9CA12LMNA | |
| SCHEMBL8869848 | 0.78 | CYP1A2 (0.45) | CA1CA2CA9CA12MEN1 | |
| SCHEMBL14380636 | 0.75 | CA2 (0.66) | CA1CA2CA9CA12MEN1 | |
| SCHEMBL5000718 | 0.73 | MAPT (0.43) | CA1CA2CA9MEN1KMT2A | |
| SCHEMBL677620 | 0.72 | ALDH1A1 (0.50) | MEN1KMT2ANSD2LMNA | |
| SCHEMBL22388775 | 0.70 | CA1 (0.71) | CA1CA2CA9KMT2ANSD2 | |
| SCHEMBL20946426 | 0.70 | CA1 (0.77) | CA1CA2CA9CA12MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679670-A | CONTROLLING INTRAOCULAR PRESSURE | ALCON LABORATORIES, INC. (US) | 1997-10-21 | — | — | US | disclosed |
| US-5378703-A | FOR CONTROLLING INTRAOCULAR PRESSURE | ALCON LABORATORIES, INC. (US) | 1995-01-03 | — | — | US | disclosed |