Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870101 | 0.83 | GUSB (0.48) | CYP1A2CYP3A4CYP2C9CYP2C19CA2 | |
| SCHEMBL8868917 | 0.78 | CA1 (0.61) | CA2CA12CA1CA9GALR3 | |
| SCHEMBL680127 | 0.74 | CA12 (0.56) | CA2CA12CA1CA9LMNA | |
| SCHEMBL8870068 | 0.74 | CA2 (0.56) | CA2CA12CA1CA9GALR3 | |
| SCHEMBL677620 | 0.71 | ALDH1A1 (0.50) | LMNAGUSBALDH1A1MEN1KMT2A | |
| SCHEMBL5226758 | 0.70 | VCAM1 (0.44) | CYP1A2CYP3A4CYP2C9CYP2C19CA2 | |
| SCHEMBL3924460 | 0.68 | CYP19A1 (0.67) | LMNACYP19A1ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9265287 | 0.68 | CA2 (0.54) | CA2HTTKDM4EALDH1A1KMT2A | |
| SCHEMBL9275311 | 0.67 | TP53 (0.41) | CYP3A4CA2CA1CA9LMNA | |
| SCHEMBL7512043 | 0.66 | L3MBTL1 (0.44) | CA2CA12CA1CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679670-A | CONTROLLING INTRAOCULAR PRESSURE | ALCON LABORATORIES, INC. (US) | 1997-10-21 | — | — | US | disclosed |
| US-5378703-A | FOR CONTROLLING INTRAOCULAR PRESSURE | ALCON LABORATORIES, INC. (US) | 1995-01-03 | — | — | US | disclosed |