Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869848 | 0.83 | CYP1A2 (0.45) | GUSBCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8868917 | 0.78 | CA1 (0.61) | CA12CA1CA2CA9LMNA | |
| SCHEMBL8870068 | 0.75 | CA2 (0.56) | CNR1POLBCA12CA1CA2 | |
| SCHEMBL680127 | 0.75 | CA12 (0.56) | CNR1POLBCA12CA1CA2 | |
| SCHEMBL28113721 | 0.72 | CA12 (0.63) | CNR1CYP3A4CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL9265287 | 0.70 | CA2 (0.54) | CA2HTTKDM4EALDH1A1MAPT | |
| SCHEMBL10487801 | 0.70 | CNR1 (0.54) | CNR1LMNATP53MAPT | |
| SCHEMBL28004243 | 0.70 | CYP19A1 (0.68) | CNR1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3918546 | 0.70 | CYP19A1 (0.68) | CNR1LMNAALDH1A1MAPT | |
| SCHEMBL677620 | 0.69 | ALDH1A1 (0.50) | GUSBPOLBTDP1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679670-A | CONTROLLING INTRAOCULAR PRESSURE | ALCON LABORATORIES, INC. (US) | 1997-10-21 | — | — | US | disclosed |
| US-5378703-A | FOR CONTROLLING INTRAOCULAR PRESSURE | ALCON LABORATORIES, INC. (US) | 1995-01-03 | — | — | US | disclosed |