Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12041029 | 0.80 | NAAA (0.60) | TSHRHTTHPGDPOLBSMN1; SMN2 | |
| SCHEMBL6540287 | 0.80 | HTT (0.57) | TSHRHTTHPGDPOLBSMN1; SMN2 | |
| SCHEMBL23222214 | 0.78 | ALDH1A1 (0.56) | TSHRHTTHPGDSMN1; SMN2HDAC3 | |
| SCHEMBL6539603 | 0.76 | KMT2A (0.53) | TSHRHTTHPGDL3MBTL1CA1 | |
| SCHEMBL12608926 | 0.75 | HCRTR1 (0.51) | TSHRHTTHPGDALDH1A1NPSR1 | |
| SCHEMBL5709109 | 0.74 | L3MBTL1 (0.60) | POLBSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL14583013 | 0.74 | HDAC3 (0.42) | TSHRHTTHPGDSMN1; SMN2NLRP3 | |
| SCHEMBL12608932 | 0.73 | KDM4E (0.57) | TSHRHTTHPGDPOLBSMN1; SMN2 | |
| SCHEMBL6461738 | 0.73 | CTSD (0.50) | NPC1RAB9ACA1CA2CA9 | |
| SCHEMBL15344057 | 0.72 | HCRTR1 (0.52) | TSHRHPGDCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602150-A | TREATMENT OF SCHIZOPHRENIA WITH REDUCED SIDE EFFECTS | RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC. (US) | 1997-02-11 | — | — | US | claimed |
| US-5602150-A | TREATMENT OF SCHIZOPHRENIA WITH REDUCED SIDE EFFECTS | RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC. (US) | 1997-02-11 | — | — | US | disclosed |