Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.60 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.59 |
| ▸ | EGFR | P00533 | 3/20 | 0.54 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.48 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.48 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767482 | 0.78 | PTGS2 (0.58) | PTGS2PTGS1P4HTMEGFRALKBH2 | |
| SCHEMBL16421191 | 0.77 | P4HTM (0.74) | PTGS2PTGS1P4HTMEGFRMEN1 | |
| Hydrochloric Acid SCHEMBL8915942 | 0.77 | PTGS2 (0.56) | PTGS2PTGS1P4HTMEGFRALKBH2 | |
| SCHEMBL8875655 | 0.77 | PTGS2 (0.56) | PTGS2PTGS1P4HTMEGFRALKBH2 | |
| SCHEMBL7318528 | 0.75 | PTGS2 (0.57) | PTGS2PTGS1P4HTMEGFRALKBH2 | |
| SCHEMBL12489988 | 0.74 | MEN1 (0.66) | PTGS2PTGS1P4HTMEGFRMEN1 | |
| SCHEMBL9018463 | 0.74 | P4HTM (1.00) | PTGS2PTGS1P4HTMEGFRALKBH2 | |
| SCHEMBL2219734 | 0.74 | NNMT (0.46) | LMNA | |
| SCHEMBL6159253 | 0.74 | PTGS2 (0.63) | PTGS2PTGS1P4HTMEGFRMEN1 | |
| SCHEMBL8915935 | 0.72 | PTGS2 (0.51) | PTGS2PTGS1P4HTMEGFRALKBH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |